STRINGSTRING
JG24_04255 protein (Klebsiella pneumoniae) - STRING interaction network
"JG24_04255" - Trigger factor in Klebsiella pneumoniae
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
JG24_04255Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation (432 aa)    
Predicted Functional Partners:
rplW
50S ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (100 aa)
   
 
  0.961
rpmC
50S ribosomal protein L29; One of the stabilizing components for the large ribosomal subunit; Derived by automated computational analysis using gene prediction method- Protein Homology (63 aa)
 
 
  0.954
tsf
Elongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (283 aa)
 
 
  0.904
clpP
ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins; Belongs to the peptidase S14 family (207 aa)
 
 
  0.888
clpX
ATP-dependent Clp protease ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (424 aa)
 
   
  0.861
rplX
50S ribosomal protein L24; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (104 aa)
   
 
  0.850
JG24_26800
Ribosomal protein; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the universal ribosomal protein uL1 family (234 aa)
 
 
  0.845
rplU
50S ribosomal protein L21; Derived by automated computational analysis using gene prediction method- Protein Homology (103 aa)
 
   
  0.828
JG24_04270
Endopeptidase La; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the peptidase S16 family (784 aa)
   
 
  0.819
JG24_04280
Peptidylprolyl isomerase; Derived by automated computational analysis using gene prediction method- Protein Homology (624 aa)
 
 
  0.811
Your Current Organism:
Klebsiella pneumoniae
NCBI taxonomy Id: 573
Other names: ATCC 13883, Bacillus pneumoniae, Bacterium pneumoniae crouposae, CCUG 225, CIP 82.91, DSM 30104, HAMBI 450, Hyalococcus pneumoniae, IFO 14940, K. pneumoniae, Klebsiella pneumoniae, Klebsiella sp. M-AI-2, Klebsiella sp. PB12, Klebsiella sp. RCE-7, LMG 2095, NBRC 14940, NCTC 9633
Server load: low (9%) [HD]