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JG24_04770 protein (Klebsiella pneumoniae) - STRING interaction network
"JG24_04770" - Citrate synthase in Klebsiella pneumoniae
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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JG24_04770Citrate synthase (Si); Type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; Derived by automated computational analysis using gene prediction method- Protein Homology (434 aa)    
Predicted Functional Partners:
JG24_09595
Aconitate hydratase; Catalyzes the conversion of citrate to isocitrate; Derived by automated computational analysis using gene prediction method- Protein Homology (890 aa)
 
  0.983
JG24_10255
Pyruvate-flavodoxin oxidoreductase; Derived by automated computational analysis using gene prediction method- Protein Homology (1175 aa)
   
 
  0.974
JG24_30060
Aconitate hydratase B; Catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the aconitase/IPM isomerase family (865 aa)
 
 
  0.972
JG24_23110
Oxidizes malate to oxaloacetate; Derived by automated computational analysis using gene prediction method- Protein Homology (312 aa)
   
  0.961
gltB
Glutamate synthase [NADPH] large chain; Catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate; Derived by automated computational analysis using gene prediction method- Protein Homology (1486 aa)
   
 
  0.953
aceF
E2 component of pyruvate dehydrogenase multienzyme complex; in Escherichia coli AceF contains three N-terminal lipoyl domains; Derived by automated computational analysis using gene prediction method- Protein Homology (632 aa)
   
  0.953
JG24_03495
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex; Derived by automated computational analysis using gene prediction method- Protein Homology (511 aa)
   
  0.953
JG24_18510
NADP-dependent malic enzyme; NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate; Derived by automated computational analysis using gene prediction method- Protein Homology (759 aa)
 
 
  0.952
fumC
Fumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily (466 aa)
     
  0.945
JG24_17600
Probable malate-quinone oxidoreductase; Derived by automated computational analysis using gene prediction method- Protein Homology (544 aa)
   
 
  0.935
Your Current Organism:
Klebsiella pneumoniae
NCBI taxonomy Id: 573
Other names: ATCC 13883, Bacillus pneumoniae, Bacterium pneumoniae crouposae, CCUG 225, CIP 82.91, DSM 30104, HAMBI 450, Hyalococcus pneumoniae, IFO 14940, K. pneumoniae, Klebsiella pneumoniae, Klebsiella sp. M-AI-2, Klebsiella sp. PB12, Klebsiella sp. RCE-7, LMG 2095, NBRC 14940, NCTC 9633
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