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tcuB protein (Klebsiella pneumoniae) - STRING interaction network
"tcuB" - With CitA in Klebsiella pneumoniae
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
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Textmining
[Homology]
Score
tcuBWith CitA (TcuA) catalyzes the oxidation of tricarballylate to cis-aconitate; originally thought to be involved in citrate utilization; Derived by automated computational analysis using gene prediction method- Protein Homology (379 aa)    
Predicted Functional Partners:
JG24_05960
Catalyzes the oxidation of tricarballylate to cis-aconitate; FAD-dependent; required for the utilization of tricarballylate as a carbon and energy source by S. enterica; Derived by automated computational analysis using gene prediction method- Protein Homology (467 aa)
 
  0.995
JG24_10255
Pyruvate-flavodoxin oxidoreductase; Derived by automated computational analysis using gene prediction method- Protein Homology (1175 aa)
   
   
  0.941
JG24_16630
Derived by automated computational analysis using gene prediction method- Protein Homology (1171 aa)
   
   
  0.940
gltB
Glutamate synthase [NADPH] large chain; Catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate; Derived by automated computational analysis using gene prediction method- Protein Homology (1486 aa)
   
      0.931
JG24_05965
Derived by automated computational analysis using gene prediction method- Protein Homology (308 aa)
 
        0.925
JG24_05950
TcuC- integral membrane protein used to transport tricarballylate across the cell membrane; Is involved in the uptake of citrate and the transport of protons into the cell; Derived by automated computational analysis using gene prediction method- Protein Homology (431 aa)
 
        0.753
sucD
Succinate--CoA ligase [ADP-forming] subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit (289 aa)
   
   
  0.726
JG24_14750
Catalyzes the formation of phosphoenolpyruvate from pyruvate; Derived by automated computational analysis using gene prediction method- Protein Homology (792 aa)
         
  0.669
JG24_04185
Proposed role in polysaccahride synthesis; Derived by automated computational analysis using gene prediction method- Protein Homology (563 aa)
 
 
  0.660
JG24_04195
Derived by automated computational analysis using gene prediction method- Protein Homology (558 aa)
 
 
  0.641
Your Current Organism:
Klebsiella pneumoniae
NCBI taxonomy Id: 573
Other names: ATCC 13883, Bacillus pneumoniae, Bacterium pneumoniae crouposae, CCUG 225, CIP 82.91, DSM 30104, HAMBI 450, Hyalococcus pneumoniae, IFO 14940, K. pneumoniae, Klebsiella pneumoniae, Klebsiella sp. M-AI-2, Klebsiella sp. PB12, Klebsiella sp. RCE-7, LMG 2095, NBRC 14940, NCTC 9633
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