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fur protein (Klebsiella pneumoniae) - STRING interaction network
"fur" - Ferric uptake regulation protein in Klebsiella pneumoniae
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
furFerric uptake regulation protein; Negatively regulates a number of operons that encode enzymes involved in iron transport; activated by manganese; forms a homodimer; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the Fur family (150 aa)    
Predicted Functional Partners:
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (354 aa)
 
     
  0.815
JG24_05975
Flavodoxin; Low-potential electron donor to a number of redox enzymes (176 aa)
   
   
  0.782
JG24_16705
Derived by automated computational analysis using gene prediction method- Protein Homology (176 aa)
   
   
  0.640
feoB
Ferrous iron transport protein B; Probable transporter of a GTP-driven Fe(2+) uptake system (772 aa)
         
  0.625
csrA
Carbon storage regulator homolog; Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (61 aa)
           
  0.574
birA
Bifunctional ligase/repressor BirA; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5’-adenylate (BirA-bio- 5’-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon (320 aa)
         
  0.571
JG24_23510
Bacterioferritin; Iron-storage protein (158 aa)
         
  0.551
hfq
RNA-binding protein Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (102 aa)
   
     
  0.546
JG24_05965
Derived by automated computational analysis using gene prediction method- Protein Homology (308 aa)
   
        0.545
JG24_21190
Flavodoxin; Low-potential electron donor to a number of redox enzymes (173 aa)
   
   
  0.519
Your Current Organism:
Klebsiella pneumoniae
NCBI taxonomy Id: 573
Other names: ATCC 13883, Bacillus pneumoniae, Bacterium pneumoniae crouposae, CCUG 225, CIP 82.91, DSM 30104, HAMBI 450, Hyalococcus pneumoniae, IFO 14940, K. pneumoniae, Klebsiella pneumoniae, Klebsiella sp. M-AI-2, Klebsiella sp. PB12, Klebsiella sp. RCE-7, LMG 2095, NBRC 14940, NCTC 9633
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