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tolA protein (Klebsiella pneumoniae) - STRING interaction network
"tolA" - Inner membrane component of 7 member Tol-Pal envelope-spanning complex in Klebsiella pneumoniae
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
tolAInner membrane component of 7 member Tol-Pal envelope-spanning complex; involved in maintaining cell envelope integrity; utilized by colicins and filamentous phages for import; interacts with TolB, Pal, and through TolB to various outer membrane porins; Derived by automated computational analysis using gene prediction method- Protein Homology (445 aa)    
Predicted Functional Partners:
JG24_06155
Membrane spanning protein in TolA-TolQ-TolR complex; involved in the tonB-independent uptake of group A colicins; Derived by automated computational analysis using gene prediction method- Protein Homology (142 aa)
 
  0.982
JG24_06150
MotA/TolQ/ExbB proton channel family protein; Membrane spanning protein in TolA-TolQ-TolR complex; involved in the tonB-independent uptake of group A colicins; Derived by automated computational analysis using gene prediction method- Protein Homology (227 aa)
   
 
  0.917
tolB
Protein TolB; Involved in the TonB-independent uptake of proteins (430 aa)
   
 
  0.899
JG24_06175
Periplasmic protein that interacts with TolA; the tol-pal system is probably involved in maintaining cell envelope integrity; Derived by automated computational analysis using gene prediction method- Protein Homology (267 aa)
 
 
  0.858
JG24_06145
4-hydroxybenzoyl-CoA thioesterase family active site; Catalyzes the hydrolysis of short chain aliphatic acyl-CoA thioesters; physiological role remains unknown; involved in phospholipid metabolism; part of the Tol/Pal system of proteins that are critical for maintaining the integrity of the cell envelope components; Derived by automated computational analysis using gene prediction method- Protein Homology (134 aa)
   
   
  0.761
JG24_26300
Protein yifE; Derived by automated computational analysis using gene prediction method- Protein Homology (112 aa)
   
          0.690
JG24_06170
Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the ompA family (174 aa)
   
 
  0.683
JG24_25020
Uncharacterized protein; Derived by automated computational analysis using gene prediction method- Protein Homology (199 aa)
   
          0.668
JG24_22730
Lipoprotein that appears to be involved in cell division; interacts with the periplasmic protease Prc and may be activated by protease processing; Derived by automated computational analysis using gene prediction method- Protein Homology (294 aa)
   
          0.662
JG24_04245
Hypothetical lipoprotein YajG; Derived by automated computational analysis using gene prediction method- Protein Homology (192 aa)
   
          0.649
Your Current Organism:
Klebsiella pneumoniae
NCBI taxonomy Id: 573
Other names: ATCC 13883, Bacillus pneumoniae, Bacterium pneumoniae crouposae, CCUG 225, CIP 82.91, DSM 30104, HAMBI 450, Hyalococcus pneumoniae, IFO 14940, K. pneumoniae, Klebsiella pneumoniae, Klebsiella sp. M-AI-2, Klebsiella sp. PB12, Klebsiella sp. RCE-7, LMG 2095, NBRC 14940, NCTC 9633
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