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tolB protein (Klebsiella pneumoniae) - STRING interaction network
"tolB" - Protein TolB in Klebsiella pneumoniae
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Cooccurence
Coexpression
Experiments
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[Homology]
Score
tolBProtein TolB; Involved in the TonB-independent uptake of proteins (430 aa)    
Predicted Functional Partners:
JG24_06170
Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the ompA family (174 aa)
 
  0.998
JG24_06155
Membrane spanning protein in TolA-TolQ-TolR complex; involved in the tonB-independent uptake of group A colicins; Derived by automated computational analysis using gene prediction method- Protein Homology (142 aa)
 
  0.979
JG24_06175
Periplasmic protein that interacts with TolA; the tol-pal system is probably involved in maintaining cell envelope integrity; Derived by automated computational analysis using gene prediction method- Protein Homology (267 aa)
 
   
  0.970
JG24_06150
MotA/TolQ/ExbB proton channel family protein; Membrane spanning protein in TolA-TolQ-TolR complex; involved in the tonB-independent uptake of group A colicins; Derived by automated computational analysis using gene prediction method- Protein Homology (227 aa)
 
 
  0.948
tolA
Inner membrane component of 7 member Tol-Pal envelope-spanning complex; involved in maintaining cell envelope integrity; utilized by colicins and filamentous phages for import; interacts with TolB, Pal, and through TolB to various outer membrane porins; Derived by automated computational analysis using gene prediction method- Protein Homology (445 aa)
   
 
  0.899
JG24_06145
4-hydroxybenzoyl-CoA thioesterase family active site; Catalyzes the hydrolysis of short chain aliphatic acyl-CoA thioesters; physiological role remains unknown; involved in phospholipid metabolism; part of the Tol/Pal system of proteins that are critical for maintaining the integrity of the cell envelope components; Derived by automated computational analysis using gene prediction method- Protein Homology (134 aa)
   
   
  0.776
bamA
Outer membrane protein assembly factor BamA; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constitutes, with BamD, the core component of the assembly machinery (809 aa)
   
 
  0.763
bamD
Outer membrane protein assembly factor BamD; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constitutes, with BamA, the core component of the assembly machinery (245 aa)
 
 
 
  0.758
JG24_27270
Part of a complex with YfgL, YfiO, and NlpB involved in outer membrane protein biosynthesis; involved in the assembly of outer membrane proteins; Derived by automated computational analysis using gene prediction method- Protein Homology (807 aa)
   
 
  0.751
lptD
LPS-assembly protein LptD; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane (782 aa)
   
   
  0.743
Your Current Organism:
Klebsiella pneumoniae
NCBI taxonomy Id: 573
Other names: ATCC 13883, Bacillus pneumoniae, Bacterium pneumoniae crouposae, CCUG 225, CIP 82.91, DSM 30104, HAMBI 450, Hyalococcus pneumoniae, IFO 14940, K. pneumoniae, Klebsiella pneumoniae, Klebsiella sp. M-AI-2, Klebsiella sp. PB12, Klebsiella sp. RCE-7, LMG 2095, NBRC 14940, NCTC 9633
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