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dinG protein (Klebsiella pneumoniae) - STRING interaction network
"dinG" - ATP-dependent helicase DinG/Rad3 in Klebsiella pneumoniae
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dinGATP-dependent helicase DinG/Rad3; Helicase involved in DNA repair and perhaps also replication; Derived by automated computational analysis using gene prediction method- Protein Homology (718 aa)    
Predicted Functional Partners:
xseA
Exodeoxyribonuclease VII large subunit; Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides; Derived by automated computational analysis using gene prediction method- Protein Homology (463 aa)
 
   
  0.768
JG24_06610
Anthranilate phosphoribosyltransferase like; Derived by automated computational analysis using gene prediction method- Protein Homology (322 aa)
     
      0.760
xseB
Exodeoxyribonuclease 7 small subunit; Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family (80 aa)
   
     
  0.758
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5’-3’ exonuclease activity (930 aa)
   
 
  0.644
dinB
DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3’-5’ exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII (351 aa)
   
   
  0.628
JG24_17455
ATP-dependent RNA helicase YejH; Derived by automated computational analysis using gene prediction method- Protein Homology (585 aa)
 
 
  0.621
rpsU
30S ribosomal protein S21; A small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the bacterial ribosomal protein bS21 family (71 aa)
           
  0.609
recX
Regulatory protein RecX; Modulates RecA activity (166 aa)
         
  0.590
rpmJ
50S ribosomal protein L36; Smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group do not have the motif; Derived by automated computational analysis using gene prediction method- Protein Homology (46 aa)
         
  0.579
JG24_30445
Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (199 aa)
     
   
  0.575
Your Current Organism:
Klebsiella pneumoniae
NCBI taxonomy Id: 573
Other names: ATCC 13883, Bacillus pneumoniae, Bacterium pneumoniae crouposae, CCUG 225, CIP 82.91, DSM 30104, HAMBI 450, Hyalococcus pneumoniae, IFO 14940, K. pneumoniae, Klebsiella pneumoniae, Klebsiella sp. M-AI-2, Klebsiella sp. PB12, Klebsiella sp. RCE-7, LMG 2095, NBRC 14940, NCTC 9633
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