STRINGSTRING
JG24_06770 protein (Klebsiella pneumoniae) - STRING interaction network
"JG24_06770" - Is involved in the formation of active molybdenum cofactor and the chelation of molybdenum in Klebsiella pneumoniae
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
JG24_06770Is involved in the formation of active molybdenum cofactor and the chelation of molybdenum; Derived by automated computational analysis using gene prediction method- Protein Homology (411 aa)    
Predicted Functional Partners:
mobA
Molybdenum cofactor guanylyltransferase; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor; Belongs to the MobA family (193 aa)
  0.999
mogA
Molybdopterin biosynthesis Mog protein,molybdochelatase; Forms a trimer; related to eukaryotic protein gephyrin; functions during molybdenum cofactor biosynthesis; Derived by automated computational analysis using gene prediction method- Protein Homology (195 aa)
  0.998
JG24_06500
Molybdenum cofactor biosynthesis protein B; May be involved in the biosynthesis of molybdopterin (170 aa)
  0.997
JG24_25770
Molybdopterin-guanine dinucleotide biosynthesis protein MobB; In Escherichia coli the MobB protein is not essential but has been found to interact with multiple proteins involved in the molybdopterin guanine dinucleotide cofactor biosynthesis pathway; Derived by automated computational analysis using gene prediction method- Protein Homology (168 aa)
 
  0.992
JG24_06765
Derived by automated computational analysis using gene prediction method- Protein Homology (251 aa)
   
  0.955
moaC
Cyclic pyranopterin monophosphate synthase; Catalyzes the conversion of (8S)-3’,8-cyclo-7,8- dihydroguanosine 5’-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family (162 aa)
 
  0.955
moaA
GTP 3’,8-cyclase; Catalyzes the cyclization of GTP to (8S)-3’,8-cyclo-7,8- dihydroguanosine 5’-triphosphate; Belongs to the radical SAM superfamily. MoaA family (329 aa)
 
 
  0.938
moaE
Molybdopterin guanine dinucleotide biosynthesis protein MoaE; Catalyzes the conversion of molybdopterin precursor Z into molybdopterin; Derived by automated computational analysis using gene prediction method- Protein Homology (150 aa)
 
   
  0.920
modA
Molybdenum ABC transporter, periplasmic molybdenum-binding protein ModA (TC 3.A.1.8.1); With ModCB is involved in the high-affinity transport of molybdate; Derived by automated computational analysis using gene prediction method- Protein Homology (257 aa)
 
     
  0.824
JG24_06280
Represses the modABCD operon and activates the moaABCD and napFDAGHBC operons; Derived by automated computational analysis using gene prediction method- Protein Homology (262 aa)
 
   
  0.806
Your Current Organism:
Klebsiella pneumoniae
NCBI taxonomy Id: 573
Other names: ATCC 13883, Bacillus pneumoniae, Bacterium pneumoniae crouposae, CCUG 225, CIP 82.91, DSM 30104, HAMBI 450, Hyalococcus pneumoniae, IFO 14940, K. pneumoniae, Klebsiella pneumoniae, Klebsiella sp. M-AI-2, Klebsiella sp. PB12, Klebsiella sp. RCE-7, LMG 2095, NBRC 14940, NCTC 9633
Server load: low (7%) [HD]