STRINGSTRING
rlmL protein (Klebsiella pneumoniae) - STRING interaction network
"rlmL" - Catalyzes the N2-methyl guanosine modification of the G2445 residue of 23S rRNA in Klebsiella pneumoniae
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rlmLCatalyzes the N2-methyl guanosine modification of the G2445 residue of 23S rRNA; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the methyltransferase superfamily (701 aa)    
Predicted Functional Partners:
JG24_07370
ABC transporter ATP-binding protein uup; Uup; in Escherichia coli this cytoplasmic protein was shown to contain ATPase activity; mutations in this gene affect RecA-independent excision of transposons and affects Mu bacteriophage growth; Derived by automated computational analysis using gene prediction method- Protein Homology (635 aa)
   
  0.936
JG24_07380
Paraquat-inducible protein B; Derived by automated computational analysis using gene prediction method- Protein Homology (545 aa)
              0.864
JG24_07385
Derived by automated computational analysis using gene prediction method- Protein Homology (187 aa)
              0.862
thiI
tRNA sulfurtransferase; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (482 aa)
 
   
  0.828
JG24_07375
Paraquat-inducible protein A; Derived by automated computational analysis using gene prediction method- Protein Homology (422 aa)
              0.813
JG24_21620
UPF0313 protein; Derived by automated computational analysis using gene prediction method- Protein Homology (727 aa)
   
   
  0.776
mnmC
FAD-dependent oxidoreductase; 5-methylaminomethyl-2-thiouridine-forming enzyme methyltransferase/FAD-dependent demodification enzyme; Derived by automated computational analysis using gene prediction method- Protein Homology (662 aa)
   
 
  0.750
JG24_07360
Flavodoxin reductases (Ferredoxin-NADPH reductases) family 1; Derived by automated computational analysis using gene prediction method- Protein Homology (369 aa)
   
        0.741
JG24_21740
Bifunctional protein HldE; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose; In the N-terminal section; belongs to the carbohydrate kinase PfkB family (477 aa)
     
        0.727
prmA
Ribosomal protein L11 methyltransferase; Methylates ribosomal protein L11 (293 aa)
 
     
  0.726
Your Current Organism:
Klebsiella pneumoniae
NCBI taxonomy Id: 573
Other names: ATCC 13883, Bacillus pneumoniae, Bacterium pneumoniae crouposae, CCUG 225, CIP 82.91, DSM 30104, HAMBI 450, Hyalococcus pneumoniae, IFO 14940, K. pneumoniae, Klebsiella pneumoniae, Klebsiella sp. M-AI-2, Klebsiella sp. PB12, Klebsiella sp. RCE-7, LMG 2095, NBRC 14940, NCTC 9633
Server load: low (6%) [HD]