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fabA protein (Klebsiella pneumoniae) - STRING interaction network
"fabA" - 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase in Klebsiella pneumoniae
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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fabA3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase; Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16-0, being most active on intermediate chain length (172 aa)    
Predicted Functional Partners:
JG24_09665
Enoyl-[acyl-carrier-protein] reductase [NADH]; Catalyzes a key regulatory step in fatty acid biosynthesis; Derived by automated computational analysis using gene prediction method- Protein Homology (262 aa)
   
 
  0.983
fabG
3-oxoacyl-[acyl-carrier protein] reductase; Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; Derived by automated computational analysis using gene prediction method- Protein Homology (244 aa)
   
  0.980
JG24_30430
(3R)-hydroxymyristoyl-[acyl carrier protein] dehydratase; Derived by automated computational analysis using gene prediction method- Protein Homology (151 aa)
     
 
  0.958
acpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis (78 aa)
   
 
  0.932
JG24_12460
Derived by automated computational analysis using gene prediction method- Protein Homology (325 aa)
   
 
  0.918
JG24_18060
3-oxoacyl-[acyl-carrier-protein] synthase, KASI; FabB, beta-Ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis- addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; Derived by automated computational analysis using gene prediction method- Protein Homology (406 aa)
 
  0.918
lpxA
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (262 aa)
 
   
  0.782
JG24_08190
3-oxoacyl-[acyl-carrier-protein] synthase, KASII; FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis- addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; Derived by automated computational analysis using gene prediction method- Protein Homology (413 aa)
 
 
  0.770
JG24_07400
ATP-dependent protease La Type II; Derived by automated computational analysis using gene prediction method- Protein Homology (585 aa)
   
        0.735
JG24_12550
3-oxoacyl-[acyl-carrier-protein] synthase, KASII; FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis- addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; Derived by automated computational analysis using gene prediction method- Protein Homology (424 aa)
 
 
  0.713
Your Current Organism:
Klebsiella pneumoniae
NCBI taxonomy Id: 573
Other names: ATCC 13883, Bacillus pneumoniae, Bacterium pneumoniae crouposae, CCUG 225, CIP 82.91, DSM 30104, HAMBI 450, Hyalococcus pneumoniae, IFO 14940, K. pneumoniae, Klebsiella pneumoniae, Klebsiella sp. M-AI-2, Klebsiella sp. PB12, Klebsiella sp. RCE-7, LMG 2095, NBRC 14940, NCTC 9633
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