STRINGSTRING
sulA protein (Klebsiella pneumoniae) - STRING interaction network
"sulA" - Cell division inhibitor SulA in Klebsiella pneumoniae
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
sulACell division inhibitor SulA; Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1-1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division (169 aa)    
Predicted Functional Partners:
ftsZ
Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (383 aa)
       
 
  0.889
JG24_19210
DNA repair protein RecN; Derived by automated computational analysis using gene prediction method- Protein Homology (553 aa)
   
   
  0.774
JG24_21465
FIG004016- Uncharacterized protein YggN; Derived by automated computational analysis using gene prediction method- Protein Homology (239 aa)
   
          0.774
JG24_30090
Predicted chaperone lipoprotein YacC, potentially involved in protein secretion; Derived by automated computational analysis using gene prediction method- Protein Homology (115 aa)
   
          0.757
JG24_04465
Putative inner membrane protein; Derived by automated computational analysis using gene prediction method- Protein Homology (156 aa)
   
          0.741
JG24_24315
Derived by automated computational analysis using gene prediction method- Protein Homology (500 aa)
   
          0.738
JG24_23755
IgaA- a membrane protein that prevents overactivation of the Rcs regulatory system; Derived by automated computational analysis using gene prediction method- Protein Homology (709 aa)
   
          0.719
JG24_10280
Uncharacterized protein; Derived by automated computational analysis using gene prediction method- Protein Homology (879 aa)
   
          0.709
JG24_18400
Predicted outer membrane lipoprotein YfeY; Derived by automated computational analysis using gene prediction method- Protein Homology (191 aa)
   
          0.702
JG24_30065
UPF0231 protein; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the UPF0231 family (120 aa)
   
          0.676
Your Current Organism:
Klebsiella pneumoniae
NCBI taxonomy Id: 573
Other names: ATCC 13883, Bacillus pneumoniae, Bacterium pneumoniae crouposae, CCUG 225, CIP 82.91, DSM 30104, HAMBI 450, Hyalococcus pneumoniae, IFO 14940, K. pneumoniae, Klebsiella pneumoniae, Klebsiella sp. M-AI-2, Klebsiella sp. PB12, Klebsiella sp. RCE-7, LMG 2095, NBRC 14940, NCTC 9633
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