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pflD protein (Klebsiella pneumoniae) - STRING interaction network
"pflD" - Involved in production of D-lactate from glucose under microaerobic conditions in Klebsiella pneumoniae
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
Cooccurence
Coexpression
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Textmining
[Homology]
Score
pflDInvolved in production of D-lactate from glucose under microaerobic conditions; cytoplasmic protein; Derived by automated computational analysis using gene prediction method- Protein Homology (765 aa)    
Predicted Functional Partners:
JG24_07545
Derived by automated computational analysis using gene prediction method- Protein Homology (291 aa)
   
  0.982
JG24_07540
FrwD with FrwB, FrwC and PtsA forms a PEP-dependent sugar phosphotransferase system permease which may phosphorylate and transport sugars into the cell; phosphorylated by EIIA; FrwB homolog; Derived by automated computational analysis using gene prediction method- Protein Homology (113 aa)
 
        0.891
JG24_06760
Pyruvate formate-lyase activating enzyme; Derived by automated computational analysis using gene prediction method- Protein Homology (299 aa)
   
  0.834
JG24_28765
Derived by automated computational analysis using gene prediction method- Protein Homology (315 aa)
   
  0.802
JG24_07555
FrwB with FrwC, FrwD and PtsA forms a PEP-dependent sugar phosphotransferase system (PTS) permease which may phosphorylate and transport sugars into the cell; cytoplasmic protein that interacts with complex EIIA; contains the second phosphorylation site of the PTS; Derived by automated computational analysis using gene prediction method- Protein Homology (106 aa)
            0.753
pflA
Pyruvate formate-lyase-activating enzyme; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5’-deoxy-adenosine; Belongs to the organic radical-activating enzymes family (246 aa)
   
  0.719
JG24_19020
Pyruvate formate-lyase; Stress-induced glycyl radical protein that can replace an oxidatively damaged pyruvate formate-lyase subunit; Derived by automated computational analysis using gene prediction method- Protein Homology (127 aa)
   
 
  0.647
JG24_07560
Derived by automated computational analysis using gene prediction method- Protein Homology (358 aa)
              0.643
JG24_16630
Derived by automated computational analysis using gene prediction method- Protein Homology (1171 aa)
         
  0.632
JG24_10255
Pyruvate-flavodoxin oxidoreductase; Derived by automated computational analysis using gene prediction method- Protein Homology (1175 aa)
         
  0.611
Your Current Organism:
Klebsiella pneumoniae
NCBI taxonomy Id: 573
Other names: ATCC 13883, Bacillus pneumoniae, Bacterium pneumoniae crouposae, CCUG 225, CIP 82.91, DSM 30104, HAMBI 450, Hyalococcus pneumoniae, IFO 14940, K. pneumoniae, Klebsiella pneumoniae, Klebsiella sp. M-AI-2, Klebsiella sp. PB12, Klebsiella sp. RCE-7, LMG 2095, NBRC 14940, NCTC 9633
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