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putA protein (Klebsiella pneumoniae) - STRING interaction network
"putA" - Transcriptional regulator in Klebsiella pneumoniae
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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putATranscriptional regulator; Proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichai coli this protein also self-regulates transcription via a DNA-binding domain at the N-terminus; forms dimers and is a peripherally membrane-associated protein; Derived by automated computational analysis using gene prediction method- Protein Homology (1320 aa)    
Predicted Functional Partners:
proC
Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline (269 aa)
     
  0.973
JG24_07930
Proline/sodium symporter PutP (TC 2.A.21.2.1) @ Propionate/sodium symporter; Involved in the sodium dependent uptake of proline; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the sodium-solute symporter (SSF) (TC 2.A.21) family (502 aa)
 
   
  0.970
JG24_03645
Glutamate 5-kinase / RNA-binding C-terminal domain PUA; Derived by automated computational analysis using gene prediction method- Protein Homology (367 aa)
       
  0.966
JG24_10530
Glutamate dehydrogenase; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the Glu/Leu/Phe/Val dehydrogenases family (424 aa)
 
 
  0.959
JG24_03640
Gamma-glutamyl phosphate reductase; Derived by automated computational analysis using gene prediction method- Protein Homology (417 aa)
       
  0.958
glnA
Forms a homododecamer; forms glutamine from ammonia and glutamate with the conversion of ATP to ADP and phosphate; also functions in the assimilation of ammonia; highly regulated protein controlled by the addition/removal of adenylyl groups by adenylyltransferase from specific tyrosine residues; addition of adenylyl groups results in inactivation of the enzyme; Derived by automated computational analysis using gene prediction method- Protein Homology (469 aa)
     
 
  0.957
JG24_07270
Aminotransferase; Derived by automated computational analysis using gene prediction method- Protein Homology (396 aa)
   
 
  0.954
JG24_09245
Converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer; Derived by automated computational analysis using gene prediction method- Protein Homology (447 aa)
   
 
  0.954
JG24_23015
Glutamate synthase [NADPH] small chain; Derived by automated computational analysis using gene prediction method- Protein Homology (472 aa)
     
 
  0.924
gltB
Glutamate synthase [NADPH] large chain; Catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate; Derived by automated computational analysis using gene prediction method- Protein Homology (1486 aa)
       
  0.923
Your Current Organism:
Klebsiella pneumoniae
NCBI taxonomy Id: 573
Other names: ATCC 13883, Bacillus pneumoniae, Bacterium pneumoniae crouposae, CCUG 225, CIP 82.91, DSM 30104, HAMBI 450, Hyalococcus pneumoniae, IFO 14940, K. pneumoniae, Klebsiella pneumoniae, Klebsiella sp. M-AI-2, Klebsiella sp. PB12, Klebsiella sp. RCE-7, LMG 2095, NBRC 14940, NCTC 9633
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