STRINGSTRING
pepT protein (Klebsiella pneumoniae) - STRING interaction network
"pepT" - Peptidase T in Klebsiella pneumoniae
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
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[Homology]
Score
pepTPeptidase T; Cleaves the N-terminal amino acid of tripeptides; Belongs to the peptidase M20B family (410 aa)    
Predicted Functional Partners:
mscL
Large-conductance mechanosensitive channel; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (137 aa)
 
     
  0.503
pepA
Probable cytosol aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides; Belongs to the peptidase M17 family (503 aa)
     
 
  0.499
JG24_02080
Derived by automated computational analysis using gene prediction method- Protein Homology (218 aa)
     
        0.491
gltB
Glutamate synthase [NADPH] large chain; Catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate; Derived by automated computational analysis using gene prediction method- Protein Homology (1486 aa)
           
  0.474
potA
Spermidine/putrescine import ATP-binding protein PotA; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system (378 aa)
              0.467
potB
Spermidine Putrescine ABC transporter permease component PotB (TC 3.A.1.11.1); Can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotB is a membrane component; Derived by automated computational analysis using gene prediction method- Protein Homology (285 aa)
              0.467
potD
ABC transporter, periplasmic spermidine putrescine-binding protein PotD (TC 3.A.1.11.1); Can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotD is a periplasmic component that binds the substrate; Derived by automated computational analysis using gene prediction method- Protein Homology (348 aa)
         
  0.465
potC
Can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotC is a membrane component; Derived by automated computational analysis using gene prediction method- Protein Homology (261 aa)
              0.455
JG24_18915
Catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; Derived by automated computational analysis using gene prediction method- Protein Homology (1295 aa)
       
      0.432
JG24_03360
Aminoacyl-histidine dipeptidase (Peptidase D); Catalyzes the hydrolysis of Xaa-His dipeptides; Derived by automated computational analysis using gene prediction method- Protein Homology (485 aa)
   
 
      0.413
Your Current Organism:
Klebsiella pneumoniae
NCBI taxonomy Id: 573
Other names: ATCC 13883, Bacillus pneumoniae, Bacterium pneumoniae crouposae, CCUG 225, CIP 82.91, DSM 30104, HAMBI 450, Hyalococcus pneumoniae, IFO 14940, K. pneumoniae, Klebsiella pneumoniae, Klebsiella sp. M-AI-2, Klebsiella sp. PB12, Klebsiella sp. RCE-7, LMG 2095, NBRC 14940, NCTC 9633
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