STRINGSTRING
lapA protein (Klebsiella pneumoniae) - STRING interaction network
"lapA" - Lipopolysaccharide assembly protein A in Klebsiella pneumoniae
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lapALipopolysaccharide assembly protein A; Involved in the assembly of lipopolysaccharide (LPS) (102 aa)    
Predicted Functional Partners:
lapB
Lipopolysaccharide assembly protein B; Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane (389 aa)
 
   
  0.952
JG24_09605
Derived by automated computational analysis using gene prediction method- Protein Homology (255 aa)
 
      0.760
JG24_19510
DNA-binding protein; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the histone-like protein H-NS family (133 aa)
   
          0.747
JG24_14975
DNA-binding protein H-NS; Derived by automated computational analysis using gene prediction method- Protein Homology (135 aa)
   
          0.738
JG24_25790
Thiol-disulfide interchange protein; Derived by automated computational analysis using gene prediction method- Protein Homology (207 aa)
   
     
  0.713
JG24_28985
Derived by automated computational analysis using gene prediction method- Protein Homology (153 aa)
           
  0.646
JG24_28960
Derived by automated computational analysis using gene prediction method- Protein Homology (2620 aa)
           
  0.646
JG24_00080
Derived by automated computational analysis using gene prediction method- Protein Homology (154 aa)
   
          0.636
lptE
LPS-assembly lipoprotein LptE; Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane (196 aa)
   
 
      0.634
JG24_08100
Putative lipoprotein yceB; Derived by automated computational analysis using gene prediction method- Protein Homology (186 aa)
   
          0.628
Your Current Organism:
Klebsiella pneumoniae
NCBI taxonomy Id: 573
Other names: ATCC 13883, Bacillus pneumoniae, Bacterium pneumoniae crouposae, CCUG 225, CIP 82.91, DSM 30104, HAMBI 450, Hyalococcus pneumoniae, IFO 14940, K. pneumoniae, Klebsiella pneumoniae, Klebsiella sp. M-AI-2, Klebsiella sp. PB12, Klebsiella sp. RCE-7, LMG 2095, NBRC 14940, NCTC 9633
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