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tpx protein (Klebsiella pneumoniae) - STRING interaction network
"tpx" - Peroxidase in Klebsiella pneumoniae
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tpxPeroxidase; Antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein; Derived by automated computational analysis using gene prediction method- Protein Homology (168 aa)    
Predicted Functional Partners:
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5’-3’ exonuclease activity (930 aa)
         
  0.639
JG24_09800
Catalyzes the epimerization of L-alanyl-D-glutamate to L-alanyl-L-glutamate; Derived by automated computational analysis using gene prediction method- Protein Homology (321 aa)
              0.595
katE
Catalase; Serves to protect cells from the toxic effects of hydrogen peroxide (752 aa)
     
   
  0.578
bcp
Thiol peroxidase, Bcp-type; Bacterioferritin comigratory protein; thiol peroxidase; thioredoxin-dependent; hydroperoxide peroxidase; in Escherichia coli this enzyme preferentially reduces linoleic acid hydroperoxide; contains an active site cysteine; Derived by automated computational analysis using gene prediction method- Protein Homology (156 aa)
 
   
  0.576
JG24_16675
Derived by automated computational analysis using gene prediction method- Protein Homology (279 aa)
   
   
  0.557
JG24_16630
Derived by automated computational analysis using gene prediction method- Protein Homology (1171 aa)
         
  0.541
JG24_07085
Thioredoxin reductase; Catalyzes the transfer of electrons from NADPH to thioredoxin; FAD/NAD(P) binding; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family (322 aa)
   
   
  0.531
JG24_16705
Derived by automated computational analysis using gene prediction method- Protein Homology (176 aa)
     
   
  0.524
JG24_05975
Flavodoxin; Low-potential electron donor to a number of redox enzymes (176 aa)
     
   
  0.524
trxA
Thioredoxin; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the thioredoxin family (109 aa)
     
 
  0.517
Your Current Organism:
Klebsiella pneumoniae
NCBI taxonomy Id: 573
Other names: ATCC 13883, Bacillus pneumoniae, Bacterium pneumoniae crouposae, CCUG 225, CIP 82.91, DSM 30104, HAMBI 450, Hyalococcus pneumoniae, IFO 14940, K. pneumoniae, Klebsiella pneumoniae, Klebsiella sp. M-AI-2, Klebsiella sp. PB12, Klebsiella sp. RCE-7, LMG 2095, NBRC 14940, NCTC 9633
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