STRINGSTRING
JG24_12470 protein (Klebsiella pneumoniae) - STRING interaction network
"JG24_12470" - Serine--pyruvate aminotransferase / L-alanine:glyoxylate aminotransferase in Klebsiella pneumoniae
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
JG24_12470Serine--pyruvate aminotransferase / L-alanine-glyoxylate aminotransferase; Derived by automated computational analysis using gene prediction method- Protein Homology (413 aa)    
Predicted Functional Partners:
JG24_12465
Derived by automated computational analysis using gene prediction method- Protein Homology (419 aa)
 
 
    0.995
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (417 aa)
   
 
  0.865
JG24_07000
Low-specificity L-threonine aldolase; Low- specificity; catalyzes the formation of acetaldehyde and glycine from L-threonine; acts on L-threonine, L-allo-threonine, L-threo-phenylserine, and L-erythro-phenylserine; Derived by automated computational analysis using gene prediction method- Protein Homology (333 aa)
   
 
  0.856
metG
Methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily (677 aa)
   
      0.845
JG24_12475
Glutamate transport ATP-binding protein; Derived by automated computational analysis using gene prediction method- Protein Homology (245 aa)
 
          0.843
JG24_21255
Glycine dehydrogenase [decarboxylating] (Glycine cleavage system P protein); Acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; Derived by automated computational analysis using gene prediction method- Protein Homology (957 aa)
   
 
  0.842
JG24_12485
Amino acid ABC transporter, permease protein; Derived by automated computational analysis using gene prediction method- Protein Homology (221 aa)
              0.822
JG24_12480
Putative amino acid ABC transporter, permease protein; Derived by automated computational analysis using gene prediction method- Protein Homology (218 aa)
              0.822
JG24_12490
ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the bacterial solute-binding protein 3 family (261 aa)
              0.821
kbl
2-amino-3-ketobutyrate coenzyme A ligase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA (397 aa)
         
    0.800
Your Current Organism:
Klebsiella pneumoniae
NCBI taxonomy Id: 573
Other names: ATCC 13883, Bacillus pneumoniae, Bacterium pneumoniae crouposae, CCUG 225, CIP 82.91, DSM 30104, HAMBI 450, Hyalococcus pneumoniae, IFO 14940, K. pneumoniae, Klebsiella pneumoniae, Klebsiella sp. M-AI-2, Klebsiella sp. PB12, Klebsiella sp. RCE-7, LMG 2095, NBRC 14940, NCTC 9633
Server load: low (7%) [HD]