STRINGSTRING
JG24_12945 protein (Klebsiella pneumoniae) - STRING interaction network
"JG24_12945" - NAD-dependent malic enzyme in Klebsiella pneumoniae
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
JG24_12945NAD-dependent malic enzyme; Derived by automated computational analysis using gene prediction method- Protein Homology (565 aa)    
Predicted Functional Partners:
JG24_10255
Pyruvate-flavodoxin oxidoreductase; Derived by automated computational analysis using gene prediction method- Protein Homology (1175 aa)
       
  0.964
JG24_14750
Catalyzes the formation of phosphoenolpyruvate from pyruvate; Derived by automated computational analysis using gene prediction method- Protein Homology (792 aa)
   
  0.948
JG24_23110
Oxidizes malate to oxaloacetate; Derived by automated computational analysis using gene prediction method- Protein Homology (312 aa)
 
  0.946
JG24_11200
Fumarate hydratase class I; Catalyzes the reversible hydration of fumarate to (S)- malate; Belongs to the class-I fumarase family (550 aa)
   
 
  0.935
JG24_10660
Fumarate hydratase class I; Catalyzes the reversible hydration of fumarate to (S)- malate; Belongs to the class-I fumarase family (548 aa)
   
 
  0.935
fumC
Fumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily (466 aa)
 
  0.932
ldh
Converts (S)-lactate and NAD(+) to pyruvate and NADH; Derived by automated computational analysis using gene prediction method- Protein Homology (314 aa)
   
  0.931
JG24_15930
Pyruvate kinase; Catalyzes the formation of phosphoenolpyruvate from pyruvate; Derived by automated computational analysis using gene prediction method- Protein Homology (480 aa)
   
  0.929
JG24_14610
Pyruvate kinase; Catalyzes the formation of phosphoenolpyruvate from pyruvate; Derived by automated computational analysis using gene prediction method- Protein Homology (470 aa)
   
  0.929
JG24_23075
Catalyzes the formation of pyruvate from oxaloacetate; Derived by automated computational analysis using gene prediction method- Protein Homology (589 aa)
       
  0.924
Your Current Organism:
Klebsiella pneumoniae
NCBI taxonomy Id: 573
Other names: ATCC 13883, Bacillus pneumoniae, Bacterium pneumoniae crouposae, CCUG 225, CIP 82.91, DSM 30104, HAMBI 450, Hyalococcus pneumoniae, IFO 14940, K. pneumoniae, Klebsiella pneumoniae, Klebsiella sp. M-AI-2, Klebsiella sp. PB12, Klebsiella sp. RCE-7, LMG 2095, NBRC 14940, NCTC 9633
Server load: low (8%) [HD]