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sufC protein (Klebsiella pneumoniae) - STRING interaction network
"sufC" - Part of SUF system involved in inserting iron-sulfur clusters into proteins in Klebsiella pneumoniae
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
sufCPart of SUF system involved in inserting iron-sulfur clusters into proteins; in Escherichia coli this protein forms a complex with SufBD; the SufBCD complex stimulates the cysteine desulfurase SufS in conjunction with SufE; Derived by automated computational analysis using gene prediction method- Protein Homology (248 aa)    
Predicted Functional Partners:
JG24_14645
Iron-sulfur cluster assembly protein SufB; With SufCD activates cysteine desulfurase SufS; Derived by automated computational analysis using gene prediction method- Protein Homology (495 aa)
 
  0.999
JG24_14635
Iron-sulfur cluster assembly protein SufD; With SufBC activates cysteine desulfurase SufS; Derived by automated computational analysis using gene prediction method- Protein Homology (424 aa)
 
  0.999
sufE
Cysteine desulfuration protein SufE; Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process; Belongs to the SufE family (138 aa)
 
 
  0.991
JG24_14630
Cysteine desulfurase, SufS subfamily; Derived by automated computational analysis using gene prediction method- Protein Homology (406 aa)
 
 
  0.981
sufA
Functions as a scaffold on which iron-sulfur clusters ([2Fe-2S]; [4Fe-4S]) are assembled; forms a homodimer; similar to IscA protein; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the HesB/IscA family (125 aa)
   
 
  0.923
JG24_20390
Derived by automated computational analysis using gene prediction method- Protein Homology (401 aa)
 
 
  0.880
JG24_16385
Derived by automated computational analysis using gene prediction method- Protein Homology (496 aa)
 
 
  0.876
JG24_20395
Binds and activates CsdA; Fe-S protein; Derived by automated computational analysis using gene prediction method- Protein Homology (145 aa)
 
 
  0.752
nfuA
Fe/S biogenesis protein NfuA; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins (191 aa)
   
 
  0.741
JG24_16675
Derived by automated computational analysis using gene prediction method- Protein Homology (279 aa)
   
   
  0.715
Your Current Organism:
Klebsiella pneumoniae
NCBI taxonomy Id: 573
Other names: ATCC 13883, Bacillus pneumoniae, Bacterium pneumoniae crouposae, CCUG 225, CIP 82.91, DSM 30104, HAMBI 450, Hyalococcus pneumoniae, IFO 14940, K. pneumoniae, Klebsiella pneumoniae, Klebsiella sp. M-AI-2, Klebsiella sp. PB12, Klebsiella sp. RCE-7, LMG 2095, NBRC 14940, NCTC 9633
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