STRINGSTRING
menI protein (Klebsiella pneumoniae) - STRING interaction network
"menI" - 1,4-dihydroxy-2-naphthoyl-CoA hydrolase in Klebsiella pneumoniae
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
menI1,4-dihydroxy-2-naphthoyl-CoA hydrolase; Catalyzes the hydrolysis of 1,4-dihydroxy-2-naphthoyl- CoA (DHNA-CoA) to 1,4-dihydroxy-2-naphthoate (DHNA) (136 aa)    
Predicted Functional Partners:
menB
1,4-dihydroxy-2-naphthoyl-CoA synthase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA) (285 aa)
 
   
  0.962
menA
1,4-dihydroxy-2-naphthoate octaprenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily (306 aa)
 
   
  0.936
JG24_14740
Fe-S protein, homolog of lactate dehydrogenase SO1521; Derived by automated computational analysis using gene prediction method- Protein Homology (1018 aa)
   
   
  0.912
JG24_05475
Isochorismatase [enterobactin] siderophore / Apo-aryl carrier domain of EntB; 2,3 dihydro-2,3 dihydroxybenzoate synthase; catalyzes the formation of 2,3 dihydro-2,3 dihydroxybenzoate and pyruvate from isochorismate; with Ent DEF is involved in enterobactin synthesis; Derived by automated computational analysis using gene prediction method- Protein Homology (283 aa)
   
 
  0.830
JG24_17775
Derived by automated computational analysis using gene prediction method- Protein Homology (429 aa)
 
   
  0.664
JG24_17765
Catalyzes the formation of (1 R,6 R)-2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate in menaquinone biosynthesis; Derived by automated computational analysis using gene prediction method- Protein Homology (252 aa)
 
     
  0.662
JG24_17770
SEPHCHC synthase; forms 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1- carboxylate from 2-oxoglutarate and isochorismate in menaquinone biosynthesis; Derived by automated computational analysis using gene prediction method- Protein Homology (556 aa)
 
     
  0.590
JG24_25470
Promiscuous sugar phosphatase YidA, haloacid dehalogenase-like phosphatase family; YidA; catalyzes the dephosphorylation of erythrose 4-phosphate (preferred substrate), mannose 1-phosphate and p-nitrophenyl phosphate; hydrolyzes the alpha-D-glucose-1-phosphate but not the beta form; member of the haloacid dehalogenase-like hydrolases superfamily and Cof family of proteins; Derived by automated computational analysis using gene prediction method- Protein Homology (270 aa)
 
            0.515
JG24_14745
YdiK; inner membrane protein; ydiK promoter presents a PurR sequence, suggesting that its expression is purine-regulated; unknown function; Derived by automated computational analysis using gene prediction method- Protein Homology (370 aa)
              0.515
JG24_17755
Catalyzes the dehydration of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid to form O-succinylbenzoate; Derived by automated computational analysis using gene prediction method- Protein Homology (321 aa)
 
     
  0.480
Your Current Organism:
Klebsiella pneumoniae
NCBI taxonomy Id: 573
Other names: ATCC 13883, Bacillus pneumoniae, Bacterium pneumoniae crouposae, CCUG 225, CIP 82.91, DSM 30104, HAMBI 450, Hyalococcus pneumoniae, IFO 14940, K. pneumoniae, Klebsiella pneumoniae, Klebsiella sp. M-AI-2, Klebsiella sp. PB12, Klebsiella sp. RCE-7, LMG 2095, NBRC 14940, NCTC 9633
Server load: low (8%) [HD]