STRINGSTRING
rssB protein (Klebsiella pneumoniae) - STRING interaction network
"rssB" - Regulator of RpoS in Klebsiella pneumoniae
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textmining
co-expression
protein homology
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rssBRegulator of RpoS; Regulates the turnover of the sigma S factor (RpoS) by promoting its proteolysis in exponentially growing cells. Acts by binding and delivering RpoS to the ClpXP protease. RssB is not co- degraded with RpoS, but is released from the complex and can initiate a new cycle of RpoS recognition and degradation (337 aa)    
Predicted Functional Partners:
JG24_14990
UPF0028 protein YchK; Derived by automated computational analysis using gene prediction method- Protein Homology (300 aa)
 
   
  0.885
rpoS
RNA polymerase sigma factor RpoS; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor controls a regulon of genes required for protection against external stresses; Derived by automated computational analysis using gene prediction method- Protein Homology (330 aa)
   
 
  0.844
JG24_20205
Histidine kinase; Part of the two-component regulatory system with UvrY; involved in the regulation of carbon metabolism via the csrA/csrB regulatory system; Derived by automated computational analysis using gene prediction method- Protein Homology (916 aa)
 
 
  0.791
JG24_14965
Thymidine kinase; Catalyzes the formation of thymidine 5’-phosphate from thymidine; Derived by automated computational analysis using gene prediction method- Protein Homology (205 aa)
 
            0.765
JG24_22980
Aerobic respiration control sensor protein arcB; Sensor-regulator protein which regulates the expression of many genes in response to respiratory growth conditions including anaerobic repression of the arc modulon; hybrid sensory histidine kinase in two-component regulatory system with ArcA; Derived by automated computational analysis using gene prediction method- Protein Homology (779 aa)
 
 
  0.744
envZ
Membrane-localized osmosensor; histidine kinase; in high osmolarity EnvZ autophosphorylates itself and transfers phosphoryl group to OmpR; Derived by automated computational analysis using gene prediction method- Protein Homology (451 aa)
   
 
  0.736
cpxA
Copper sensory histidine kinase CpxA; Part of two-component CpxA/CpxR system; senses envelope stress; upregulates a number of periplasmic folding and trafficking factors; Derived by automated computational analysis using gene prediction method- Protein Homology (457 aa)
   
 
  0.732
rcsD
Phosphotransferase RcsD; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsD is a phosphotransfer intermediate between the sensor kinase RcsC and the response regulator RcsB. It acquires a phosphoryl group from RcsC and transfers it to RcsB (885 aa)
 
 
  0.722
JG24_09885
Derived by automated computational analysis using gene prediction method- Protein Homology (897 aa)
 
 
  0.684
iraP
Anti-adapter protein IraP; Inhibits RpoS proteolysis by regulating RssB activity, thereby increasing the stability of the sigma stress factor RpoS especially during phosphate starvation, but also in stationary phase and during nitrogen starvation. Its effect on RpoS stability is due to its interaction with RssB, which probably blocks the interaction of RssB with RpoS, and the consequent delivery of the RssB-RpoS complex to the ClpXP protein degradation pathway (86 aa)
       
 
  0.671
Your Current Organism:
Klebsiella pneumoniae
NCBI taxonomy Id: 573
Other names: ATCC 13883, Bacillus pneumoniae, Bacterium pneumoniae crouposae, CCUG 225, CIP 82.91, DSM 30104, HAMBI 450, Hyalococcus pneumoniae, IFO 14940, K. pneumoniae, Klebsiella pneumoniae, Klebsiella sp. M-AI-2, Klebsiella sp. PB12, Klebsiella sp. RCE-7, LMG 2095, NBRC 14940, NCTC 9633
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