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JG24_15000 protein (Klebsiella pneumoniae) - STRING interaction network
"JG24_15000" - Formyltetrahydrofolate deformylase in Klebsiella pneumoniae
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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JG24_15000Formyltetrahydrofolate deformylase; Derived by automated computational analysis using gene prediction method- Protein Homology (280 aa)    
Predicted Functional Partners:
JG24_04710
Methylenetetrahydrofolate dehydrogenase (NADP+) / Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (288 aa)
 
 
  0.965
gcvT
Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine (364 aa)
   
 
  0.935
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (417 aa)
   
 
  0.932
purT
Formate-dependent phosphoribosylglycinamide formyltransferase; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family (392 aa)
       
  0.929
metH
5-methyltetrahydrofolate--homocysteine methyltransferase; One of two methionine synthases in Escherichia coli; MetH catalyzes a methyl transfer reaction from methyltetrahydrofolate to homocysteine to create methionine; requires zinc for activity; Derived by automated computational analysis using gene prediction method- Protein Homology (1227 aa)
       
  0.928
purN
Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate (213 aa)
 
 
0.923
folA
Catalyzes the reduction of dihydrofolate to tetrahydrofolate; Derived by automated computational analysis using gene prediction method- Protein Homology (159 aa)
       
  0.903
JG24_25895
Formate dehydrogenase O alpha subunit @ selenocysteine-containing; Derived by automated computational analysis using gene prediction method- Protein Homology (804 aa)
       
    0.903
JG24_25885
Formate dehydrogenase O gamma subunit; Cytochrome b556(FDO) component; heme containing; Derived by automated computational analysis using gene prediction method- Protein Homology (211 aa)
     
 
    0.901
JG24_25900
Formate dehydrogenase O alpha subunit @ selenocysteine-containing; Derived by automated computational analysis using gene prediction method- Protein Homology (195 aa)
       
    0.900
Your Current Organism:
Klebsiella pneumoniae
NCBI taxonomy Id: 573
Other names: ATCC 13883, Bacillus pneumoniae, Bacterium pneumoniae crouposae, CCUG 225, CIP 82.91, DSM 30104, HAMBI 450, Hyalococcus pneumoniae, IFO 14940, K. pneumoniae, Klebsiella pneumoniae, Klebsiella sp. M-AI-2, Klebsiella sp. PB12, Klebsiella sp. RCE-7, LMG 2095, NBRC 14940, NCTC 9633
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