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prs protein (Klebsiella pneumoniae) - STRING interaction network
"prs" - Ribose-phosphate pyrophosphokinase in Klebsiella pneumoniae
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily (315 aa)    
Predicted Functional Partners:
JG24_17980
Amidophosphoribosyltransferase; Catalyzes first step of the de novo purine nucleotide biosynthetic pathway; Derived by automated computational analysis using gene prediction method- Protein Homology (505 aa)
   
  0.956
rbsK
Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway (309 aa)
     
  0.952
glmU
N-acetylglucosamine-1-phosphate uridyltransferase / Glucosamine-1-phosphate N-acetyltransferase; Forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis; Derived by automated computational analysis using gene prediction method- Protein Homology (456 aa)
   
  0.948
rpiA
Ribose-5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate (219 aa)
   
  0.938
JG24_18520
Transketolase; Catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; Derived by automated computational analysis using gene prediction method- Protein Homology (664 aa)
 
  0.936
JG24_21355
Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate (663 aa)
 
  0.936
deoB
Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family (407 aa)
         
  0.920
JG24_06000
Phosphoglucomutase; Catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate; Derived by automated computational analysis using gene prediction method- Protein Homology (546 aa)
     
  0.919
nudE
ADP compounds hydrolase NudE; ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose; Derived by automated computational analysis using gene prediction method- Protein Homology (186 aa)
   
  0.915
nudF
ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose; Derived by automated computational analysis using gene prediction method- Protein Homology (210 aa)
   
  0.913
Your Current Organism:
Klebsiella pneumoniae
NCBI taxonomy Id: 573
Other names: ATCC 13883, Bacillus pneumoniae, Bacterium pneumoniae crouposae, CCUG 225, CIP 82.91, DSM 30104, HAMBI 450, Hyalococcus pneumoniae, IFO 14940, K. pneumoniae, Klebsiella pneumoniae, Klebsiella sp. M-AI-2, Klebsiella sp. PB12, Klebsiella sp. RCE-7, LMG 2095, NBRC 14940, NCTC 9633
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