STRINGSTRING
JG24_15450 protein (Klebsiella pneumoniae) - STRING interaction network
"JG24_15450" - Threonine dehydratase, catabolic in Klebsiella pneumoniae
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
JG24_15450Threonine dehydratase, catabolic; Catalyzes the formation of 2-oxobutanoate from L-threonine; catabolic; Derived by automated computational analysis using gene prediction method- Protein Homology (329 aa)    
Predicted Functional Partners:
JG24_29815
3-isopropylmalate dehydrogenase; Derived by automated computational analysis using gene prediction method- Protein Homology (363 aa)
 
 
  0.949
JG24_07000
Low-specificity L-threonine aldolase; Low- specificity; catalyzes the formation of acetaldehyde and glycine from L-threonine; acts on L-threonine, L-allo-threonine, L-threo-phenylserine, and L-erythro-phenylserine; Derived by automated computational analysis using gene prediction method- Protein Homology (333 aa)
   
 
  0.932
JG24_29430
Threonine synthase; Derived by automated computational analysis using gene prediction method- Protein Homology (426 aa)
   
 
  0.931
JG24_21515
Cystathionine beta-synthase; Derived by automated computational analysis using gene prediction method- Protein Homology (456 aa)
 
 
  0.929
JG24_15435
Pyruvate formate-lyase; Formate acetyltransferase; catalyzes the formation of formate and acetyl-CoA from pyruvate; Derived by automated computational analysis using gene prediction method- Protein Homology (764 aa)
   
 
    0.925
tdh
L-threonine 3-dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate; Belongs to the zinc-containing alcohol dehydrogenase family (341 aa)
       
  0.922
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (417 aa)
     
 
  0.921
JG24_09505
Catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate; Derived by automated computational analysis using gene prediction method- Protein Homology (397 aa)
     
  0.918
JG24_09500
Tryptophan synthase alpha chain; Derived by automated computational analysis using gene prediction method- Protein Homology (269 aa)
     
 
  0.915
dsdA
D-serine dehydratase; Catalyzes the formation of pyruvate from serine; Derived by automated computational analysis using gene prediction method- Protein Homology (442 aa)
         
  0.905
Your Current Organism:
Klebsiella pneumoniae
NCBI taxonomy Id: 573
Other names: ATCC 13883, Bacillus pneumoniae, Bacterium pneumoniae crouposae, CCUG 225, CIP 82.91, DSM 30104, HAMBI 450, Hyalococcus pneumoniae, IFO 14940, K. pneumoniae, Klebsiella pneumoniae, Klebsiella sp. M-AI-2, Klebsiella sp. PB12, Klebsiella sp. RCE-7, LMG 2095, NBRC 14940, NCTC 9633
Server load: low (9%) [HD]