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JG24_15695 protein (Klebsiella pneumoniae) - STRING interaction network
"JG24_15695" - UPF0181 protein in Klebsiella pneumoniae
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
JG24_15695UPF0181 protein; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the UPF0181 family (67 aa)    
Predicted Functional Partners:
matP
Macrodomain Ter protein; Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain (150 aa)
   
          0.781
mukF
Chromosome partition protein MukF; Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity (440 aa)
   
          0.743
JG24_07420
DNA transformation protein TfoX; Derived by automated computational analysis using gene prediction method- Protein Homology (198 aa)
   
          0.729
zapB
Cell division protein ZapB; Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA (79 aa)
   
          0.726
JG24_24220
ppGpp-dependent, membrane associated, stress protein produced under conditions of nutrient deprivation, osmotic shock and oxidative stress; Derived by automated computational analysis using gene prediction method- Protein Homology (111 aa)
   
          0.725
mukB
SMC (structural maintenance of chromosomes) family of proteins; involved in chromosome condensatin and partitioning; forms a homodimer and the C-terminal is essential for DNA-binding activity while the purified N-terminal domain binds FtsZ; mutations result in cell division defects; Derived by automated computational analysis using gene prediction method- Protein Homology (1482 aa)
   
          0.724
recO
Involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA; Derived by automated computational analysis using gene prediction method- Protein Homology (245 aa)
   
          0.707
JG24_07245
Acts with MukB and MukF to condense the chromosome and allow for segregation during cell division; Derived by automated computational analysis using gene prediction method- Protein Homology (234 aa)
   
          0.703
trpR
Trp operon repressor; This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5’- ACTAGT-’3’) and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region (109 aa)
   
          0.694
JG24_29270
With the chi subunit binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB; Derived by automated computational analysis using gene prediction method- Protein Homology (137 aa)
   
          0.666
Your Current Organism:
Klebsiella pneumoniae
NCBI taxonomy Id: 573
Other names: ATCC 13883, Bacillus pneumoniae, Bacterium pneumoniae crouposae, CCUG 225, CIP 82.91, DSM 30104, HAMBI 450, Hyalococcus pneumoniae, IFO 14940, K. pneumoniae, Klebsiella pneumoniae, Klebsiella sp. M-AI-2, Klebsiella sp. PB12, Klebsiella sp. RCE-7, LMG 2095, NBRC 14940, NCTC 9633
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