STRINGSTRING
proQ protein (Klebsiella pneumoniae) - STRING interaction network
"proQ" - RNA chaperone ProQ in Klebsiella pneumoniae
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
proQRNA chaperone ProQ; RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities. May regulate ProP activity through an RNA-based, post-transcriptional mechanism (225 aa)    
Predicted Functional Partners:
JG24_15805
Tail-specific protease; Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the peptidase S41A family (682 aa)
 
  0.982
JG24_22730
Lipoprotein that appears to be involved in cell division; interacts with the periplasmic protease Prc and may be activated by protease processing; Derived by automated computational analysis using gene prediction method- Protein Homology (294 aa)
   
   
  0.864
JG24_15815
Free methionine-(R)-sulfoxide reductase, contains GAF domain; Derived by automated computational analysis using gene prediction method- Protein Homology (165 aa)
 
        0.833
metJ
Met repressor; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis; Belongs to the MetJ family (105 aa)
   
     
  0.768
JG24_20720
DNA mismatch repair endonuclease MutH; MutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences during DNA repair; Derived by automated computational analysis using gene prediction method- Protein Homology (231 aa)
   
          0.766
rraB
Regulator of ribonuclease activity B; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome (140 aa)
   
          0.762
seqA
Negative modulator of initiation of replication; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (182 aa)
   
        0.756
JG24_17890
UPF0208 membrane protein; Derived by automated computational analysis using gene prediction method- Protein Homology (151 aa)
   
          0.738
dsbB
Disulfide bond formation protein B; Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (176 aa)
   
        0.717
JG24_26900
Uncharacterized protein; Derived by automated computational analysis using gene prediction method- Protein Homology (196 aa)
   
          0.712
Your Current Organism:
Klebsiella pneumoniae
NCBI taxonomy Id: 573
Other names: ATCC 13883, Bacillus pneumoniae, Bacterium pneumoniae crouposae, CCUG 225, CIP 82.91, DSM 30104, HAMBI 450, Hyalococcus pneumoniae, IFO 14940, K. pneumoniae, Klebsiella pneumoniae, Klebsiella sp. M-AI-2, Klebsiella sp. PB12, Klebsiella sp. RCE-7, LMG 2095, NBRC 14940, NCTC 9633
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