STRINGSTRING
JG24_15910 protein (Klebsiella pneumoniae) - STRING interaction network
"JG24_15910" - Phosphogluconate dehydratase in Klebsiella pneumoniae
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
JG24_15910Phosphogluconate dehydratase; Catalyzes the formation of 2-dehydro-3-deoxy-6-phospho-D-gluconate from 6-phospho-D-gluconate; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the IlvD/Edd family (603 aa)    
Predicted Functional Partners:
JG24_15905
4-hydroxy-2-oxoglutarate aldolase @ 2-dehydro-3-deoxyphosphogluconate aldolase; Catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate; Derived by automated computational analysis using gene prediction method- Protein Homology (213 aa)
 
  0.999
gntK
Gluconokinase; Thermoresistant; catalyzes the formation of 6-phospho-D-gluconate from gluconate; Derived by automated computational analysis using gene prediction method- Protein Homology (176 aa)
   
 
  0.960
zwf
Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone (491 aa)
 
   
  0.930
JG24_16865
6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the 6-phosphogluconate dehydrogenase family (468 aa)
         
  0.920
JG24_24310
Catalyzes the formation of 2-dehydro-3-deoxy-D-gluconate-6-phosphate from 2-dehydro-3-deoxy-D-gluconate; Derived by automated computational analysis using gene prediction method- Protein Homology (309 aa)
   
 
  0.919
JG24_24515
2-ketogluconate kinase; Derived by automated computational analysis using gene prediction method- Protein Homology (311 aa)
   
 
  0.909
pgl
6-phosphogluconolactonase; Catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate (331 aa)
       
    0.901
JG24_26345
Ketol-acid reductoisomerase; Catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis; Derived by automated computational analysis using gene prediction method- Protein Homology (491 aa)
 
 
  0.832
gltB
Glutamate synthase [NADPH] large chain; Catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate; Derived by automated computational analysis using gene prediction method- Protein Homology (1486 aa)
   
   
  0.812
JG24_15925
Phosphogluconate repressor HexR, RpiR family; Represses the expression of the zwf, eda, glp and gap; Derived by automated computational analysis using gene prediction method- Protein Homology (289 aa)
 
   
  0.798
Your Current Organism:
Klebsiella pneumoniae
NCBI taxonomy Id: 573
Other names: ATCC 13883, Bacillus pneumoniae, Bacterium pneumoniae crouposae, CCUG 225, CIP 82.91, DSM 30104, HAMBI 450, Hyalococcus pneumoniae, IFO 14940, K. pneumoniae, Klebsiella pneumoniae, Klebsiella sp. M-AI-2, Klebsiella sp. PB12, Klebsiella sp. RCE-7, LMG 2095, NBRC 14940, NCTC 9633
Server load: low (11%) [HD]