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sbcB protein (Klebsiella pneumoniae) - STRING interaction network
"sbcB" - Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates in Klebsiella pneumoniae
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sbcBExonucleolytic cleavage in the 3’- to 5’-direction to yield nucleoside 5’-phosphates; Derived by automated computational analysis using gene prediction method- Protein Homology (472 aa)    
Predicted Functional Partners:
JG24_20255
Decarboxylase family protein; Derived by automated computational analysis using gene prediction method- Protein Homology (455 aa)
   
          0.625
recB
Exodeoxyribonuclease V beta chain; Helicase/nuclease; with RecCD catalyzes the exonucleolytic cleavage of DNA; RecD has 5’ to 3’ helicase activity; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the helicase family. UvrD subfamily (1178 aa)
         
  0.593
JG24_21175
5’-3’ single-stranded-DNA-specific exonuclease; Derived by automated computational analysis using gene prediction method- Protein Homology (577 aa)
     
 
  0.576
rdgC
Recombination-associated protein RdgC; May be involved in recombination (303 aa)
   
     
  0.574
recF
DNA replication and repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (357 aa)
     
   
  0.532
mukB
SMC (structural maintenance of chromosomes) family of proteins; involved in chromosome condensatin and partitioning; forms a homodimer and the C-terminal is essential for DNA-binding activity while the purified N-terminal domain binds FtsZ; mutations result in cell division defects; Derived by automated computational analysis using gene prediction method- Protein Homology (1482 aa)
         
  0.530
recO
Involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA; Derived by automated computational analysis using gene prediction method- Protein Homology (245 aa)
   
     
  0.513
hslV
ATP-dependent protease subunit HslV; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (176 aa)
           
  0.506
JG24_16610
Derived by automated computational analysis using gene prediction method- Protein Homology (591 aa)
              0.505
recC
Exodeoxyribonuclease V gamma chain; Catalyzes ATP-dependent exonucleolytic cleavage in either 5’- to 3’- or 3’- to 5’-direction to yield 5’-phosphooligonucleotides; component of the RecBCD (Exo V) helicase/nuclease complex that is essential for recombination; Derived by automated computational analysis using gene prediction method- Protein Homology (1125 aa)
           
  0.501
Your Current Organism:
Klebsiella pneumoniae
NCBI taxonomy Id: 573
Other names: ATCC 13883, Bacillus pneumoniae, Bacterium pneumoniae crouposae, CCUG 225, CIP 82.91, DSM 30104, HAMBI 450, Hyalococcus pneumoniae, IFO 14940, K. pneumoniae, Klebsiella pneumoniae, Klebsiella sp. M-AI-2, Klebsiella sp. PB12, Klebsiella sp. RCE-7, LMG 2095, NBRC 14940, NCTC 9633
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