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fruK protein (Klebsiella pneumoniae) - STRING interaction network
"fruK" - 1-phosphofructokinase in Klebsiella pneumoniae
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
fruK1-phosphofructokinase; Converts fructose-1-phosphate and ATP to fructose-1,6-bisphosphate and ADP; highly specific for fructose-1-phopshate; similar to PfkB; forms homodimers; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the carbohydrate kinase PfkB family (312 aa)    
Predicted Functional Partners:
JG24_17345
PTS system, fructose-specific IIB component / PTS system, fructose-specific IIC component; Phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; Derived by automated computational analysis using gene prediction method- Protein Homology (564 aa)
 
 
  0.999
JG24_17355
Fructose-specific phosphocarrier protein HPr / PTS system, fructose-specific IIA component; Phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIA is phosphorylated by phospho-HPr which then transfers the phosphoryl group to the IIB component; Derived by automated computational analysis using gene prediction method- Protein Homology (376 aa)
 
  0.998
JG24_22600
PTS system, tagatose-specific IIBC component; Derived by automated computational analysis using gene prediction method- Protein Homology (470 aa)
 
 
  0.996
JG24_12320
Derived by automated computational analysis using gene prediction method- Protein Homology (103 aa)
 
 
  0.985
JG24_12315
PTS system, fructose-specific IIBC component; Derived by automated computational analysis using gene prediction method- Protein Homology (368 aa)
 
 
  0.985
pfkA
ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis (320 aa)
   
   
  0.954
JG24_28220
Fructose-1,6-bisphosphatase, type I; Catalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the FBPase class 1 family (332 aa)
       
  0.949
JG24_12325
PTS system, fructose-specific IIA component; Derived by automated computational analysis using gene prediction method- Protein Homology (156 aa)
 
 
  0.944
JG24_25005
Fructose-1,6-bisphosphatase, GlpX type; Derived by automated computational analysis using gene prediction method- Protein Homology (336 aa)
         
  0.943
JG24_22595
Phosphofructokinase; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the carbohydrate kinase PfkB family (304 aa)
   
   
 
0.926
Your Current Organism:
Klebsiella pneumoniae
NCBI taxonomy Id: 573
Other names: ATCC 13883, Bacillus pneumoniae, Bacterium pneumoniae crouposae, CCUG 225, CIP 82.91, DSM 30104, HAMBI 450, Hyalococcus pneumoniae, IFO 14940, K. pneumoniae, Klebsiella pneumoniae, Klebsiella sp. M-AI-2, Klebsiella sp. PB12, Klebsiella sp. RCE-7, LMG 2095, NBRC 14940, NCTC 9633
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