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JG24_17625 protein (Klebsiella pneumoniae) - STRING interaction network
"JG24_17625" - Regulates genes involved in the repair of alkylated DNA in Klebsiella pneumoniae
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second shell of interactors
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filled nodes:
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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[Homology]
Score
JG24_17625Regulates genes involved in the repair of alkylated DNA; repairs DNA containing 6-O-methylguanine; Derived by automated computational analysis using gene prediction method- Protein Homology (354 aa)    
Predicted Functional Partners:
JG24_17620
Alkylated DNA repair protein AlkB; Derived by automated computational analysis using gene prediction method- Protein Homology (217 aa)
 
   
  0.977
JG24_16945
DNA-3-methyladenine glycosylase II; Inducible, catalyzes the hydrolysis of alkylated DNA, releasing 3-methyladenine, 3-methylguanine, 7-methylguanine and 7-methyladenine; Derived by automated computational analysis using gene prediction method- Protein Homology (282 aa)
 
 
  0.964
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5’-3’ exonuclease activity (930 aa)
     
 
  0.682
JG24_17615
Putative ATP-binding component of a transport system; Efflux pump for the antibacterial peptide microcin J25; Derived by automated computational analysis using gene prediction method- Protein Homology (547 aa)
         
  0.645
JG24_17630
FAD-protein FMN transferase; Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein; Belongs to the ApbE family (350 aa)
              0.630
JG24_09300
Exodeoxyribonuclease III; Derived by automated computational analysis using gene prediction method- Protein Homology (268 aa)
         
  0.627
nth
Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3’ to the AP site by a beta-elimination, leaving a 3’-terminal unsaturated sugar and a product with a terminal 5’-phosphate (211 aa)
         
  0.598
uvrB
UvrABC system protein B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and [...] (673 aa)
     
 
  0.543
rpoH
RNA polymerase sigma factor RpoH; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes (284 aa)
     
 
  0.542
rpoD
RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth (613 aa)
     
 
  0.542
Your Current Organism:
Klebsiella pneumoniae
NCBI taxonomy Id: 573
Other names: ATCC 13883, Bacillus pneumoniae, Bacterium pneumoniae crouposae, CCUG 225, CIP 82.91, DSM 30104, HAMBI 450, Hyalococcus pneumoniae, IFO 14940, K. pneumoniae, Klebsiella pneumoniae, Klebsiella sp. M-AI-2, Klebsiella sp. PB12, Klebsiella sp. RCE-7, LMG 2095, NBRC 14940, NCTC 9633
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