STRINGSTRING
rcsD protein (Klebsiella pneumoniae) - STRING interaction network
"rcsD" - Phosphotransferase RcsD in Klebsiella pneumoniae
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Score
rcsDPhosphotransferase RcsD; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsD is a phosphotransfer intermediate between the sensor kinase RcsC and the response regulator RcsB. It acquires a phosphoryl group from RcsC and transfers it to RcsB (885 aa)    
Predicted Functional Partners:
rcsB
Transcriptional regulatory protein RcsB; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsB is the response regulator that binds to regulatory DNA regions (216 aa)
  0.998
rcsF
Outer membrane lipoprotein RcsF; Essential component of the Rcs signaling system, which controls transcription of numerous genes. Plays a role in signal transduction from the cell surface to the histidine kinase RcsC. May detect outer membrane defects (135 aa)
   
   
  0.945
rcsC
Sensor histidine kinase RcsC; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsC functions as a membrane- associated protein kinase that phosphorylates RcsD in response to environmental signals. The phosphoryl group is then transferred to the response regulator RcsB (946 aa)
 
0.941
rcsA
Transcriptional regulatory protein RcsA; Component of the Rcs signaling system, which controls transcription of numerous genes. Binds to DNA to regulate expression of genes (207 aa)
 
 
  0.941
JG24_20205
Histidine kinase; Part of the two-component regulatory system with UvrY; involved in the regulation of carbon metabolism via the csrA/csrB regulatory system; Derived by automated computational analysis using gene prediction method- Protein Homology (916 aa)
 
 
  0.876
JG24_08835
Uncharacterized protein; Derived by automated computational analysis using gene prediction method- Protein Homology (594 aa)
     
 
  0.833
JG24_23755
IgaA- a membrane protein that prevents overactivation of the Rcs regulatory system; Derived by automated computational analysis using gene prediction method- Protein Homology (709 aa)
   
   
  0.802
JG24_23195
Putative lipoprotein; Regulates the degradation of the small RNAs CsrB and CsrC; may function to targate RNase E to specific RNA molecules; Derived by automated computational analysis using gene prediction method- Protein Homology (646 aa)
 
 
  0.779
JG24_18795
Protein SseB; Enhances serine sensitivity caused by inhibition of homoserine dehydrogenase I; Derived by automated computational analysis using gene prediction method- Protein Homology (258 aa)
   
          0.774
JG24_27485
Derived by automated computational analysis using gene prediction method- Protein Homology (761 aa)
   
 
  0.739
Your Current Organism:
Klebsiella pneumoniae
NCBI taxonomy Id: 573
Other names: ATCC 13883, Bacillus pneumoniae, Bacterium pneumoniae crouposae, CCUG 225, CIP 82.91, DSM 30104, HAMBI 450, Hyalococcus pneumoniae, IFO 14940, K. pneumoniae, Klebsiella pneumoniae, Klebsiella sp. M-AI-2, Klebsiella sp. PB12, Klebsiella sp. RCE-7, LMG 2095, NBRC 14940, NCTC 9633
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