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rcsC protein (Klebsiella pneumoniae) - STRING interaction network
"rcsC" - Sensor histidine kinase RcsC in Klebsiella pneumoniae
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rcsCSensor histidine kinase RcsC; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsC functions as a membrane- associated protein kinase that phosphorylates RcsD in response to environmental signals. The phosphoryl group is then transferred to the response regulator RcsB (946 aa)    
Predicted Functional Partners:
rcsD
Phosphotransferase RcsD; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsD is a phosphotransfer intermediate between the sensor kinase RcsC and the response regulator RcsB. It acquires a phosphoryl group from RcsC and transfers it to RcsB (885 aa)
 
0.941
rcsB
Transcriptional regulatory protein RcsB; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsB is the response regulator that binds to regulatory DNA regions (216 aa)
 
 
 
  0.924
rcsF
Outer membrane lipoprotein RcsF; Essential component of the Rcs signaling system, which controls transcription of numerous genes. Plays a role in signal transduction from the cell surface to the histidine kinase RcsC. May detect outer membrane defects (135 aa)
   
   
  0.910
JG24_08835
Uncharacterized protein; Derived by automated computational analysis using gene prediction method- Protein Homology (594 aa)
     
 
  0.801
JG24_09925
Derived by automated computational analysis using gene prediction method- Protein Homology (404 aa)
 
0.750
rcsA
Transcriptional regulatory protein RcsA; Component of the Rcs signaling system, which controls transcription of numerous genes. Binds to DNA to regulate expression of genes (207 aa)
         
  0.741
JG24_16495
FOG- GGDEF domain; Derived by automated computational analysis using gene prediction method- Protein Homology (323 aa)
 
 
  0.691
JG24_20205
Histidine kinase; Part of the two-component regulatory system with UvrY; involved in the regulation of carbon metabolism via the csrA/csrB regulatory system; Derived by automated computational analysis using gene prediction method- Protein Homology (916 aa)
 
 
0.689
JG24_08420
Sensor protein PhoQ; Derived by automated computational analysis using gene prediction method- Protein Homology (488 aa)
   
 
 
  0.655
JG24_10690
Transcriptional regulatory protein RstA; Response regulator in two-component regulatory system with RstB; Derived by automated computational analysis using gene prediction method- Protein Homology (240 aa)
 
 
  0.651
Your Current Organism:
Klebsiella pneumoniae
NCBI taxonomy Id: 573
Other names: ATCC 13883, Bacillus pneumoniae, Bacterium pneumoniae crouposae, CCUG 225, CIP 82.91, DSM 30104, HAMBI 450, Hyalococcus pneumoniae, IFO 14940, K. pneumoniae, Klebsiella pneumoniae, Klebsiella sp. M-AI-2, Klebsiella sp. PB12, Klebsiella sp. RCE-7, LMG 2095, NBRC 14940, NCTC 9633
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