STRINGSTRING
flk protein (Klebsiella pneumoniae) - STRING interaction network
"flk" - In Salmonella typhimurium Flk regulates flagellar biosynthesis by inhibition of the flagellar-associated type III secretion system in Klebsiella pneumoniae
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Score
flkIn Salmonella typhimurium Flk regulates flagellar biosynthesis by inhibition of the flagellar-associated type III secretion system; lowers secretion levels of the anti-sigma28 factor FlgM to the periplasm; inner membrane-anchored protein; Derived by automated computational analysis using gene prediction method- Protein Homology (326 aa)    
Predicted Functional Partners:
ompX
Outer membrane protein X; OmpX; involved in cell adhesion; forms an eight-stranded antiparallel beta-barrel that protrudes from the cell surface; mutations in the gene increase cell-surface contact in fimbriated strains but decrease contact in nonfimbriated strains; Derived by automated computational analysis using gene prediction method- Protein Homology (171 aa)
   
          0.769
JG24_15775
Uncharacterized protein; Derived by automated computational analysis using gene prediction method- Protein Homology (96 aa)
   
          0.757
aaeB
P-hydroxybenzoic acid efflux pump subunit AaeB; Forms an efflux pump with AaeA. Could function as a metabolic relief valve, allowing to eliminate certain compounds when they accumulate to high levels in the cell (655 aa)
   
        0.756
JG24_18795
Protein SseB; Enhances serine sensitivity caused by inhibition of homoserine dehydrogenase I; Derived by automated computational analysis using gene prediction method- Protein Homology (258 aa)
   
          0.745
JG24_08230
YcfL protein- an outer membrane lipoprotein that is part of a salvage cluster; Derived by automated computational analysis using gene prediction method- Protein Homology (124 aa)
   
          0.744
mzrA
Modulator protein MzrA; Modulates the activity of the EnvZ/OmpR two-component regulatory system, probably by directly modulating EnvZ enzymatic activity and increasing stability of phosphorylated OmpR (127 aa)
   
        0.723
rcsD
Phosphotransferase RcsD; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsD is a phosphotransfer intermediate between the sensor kinase RcsC and the response regulator RcsB. It acquires a phosphoryl group from RcsC and transfers it to RcsB (885 aa)
   
          0.709
JG24_27980
Putative exported protein; In Escherichia coli, mutation of this gene affects biofilm maturation, stress response, and motility; Derived by automated computational analysis using gene prediction method- Protein Homology (102 aa)
   
          0.701
JG24_24530
Probable exported protein YPO4070; Derived by automated computational analysis using gene prediction method- Protein Homology (236 aa)
   
          0.693
JG24_23755
IgaA- a membrane protein that prevents overactivation of the Rcs regulatory system; Derived by automated computational analysis using gene prediction method- Protein Homology (709 aa)
   
          0.685
Your Current Organism:
Klebsiella pneumoniae
NCBI taxonomy Id: 573
Other names: ATCC 13883, Bacillus pneumoniae, Bacterium pneumoniae crouposae, CCUG 225, CIP 82.91, DSM 30104, HAMBI 450, Hyalococcus pneumoniae, IFO 14940, K. pneumoniae, Klebsiella pneumoniae, Klebsiella sp. M-AI-2, Klebsiella sp. PB12, Klebsiella sp. RCE-7, LMG 2095, NBRC 14940, NCTC 9633
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