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mepA protein (Klebsiella pneumoniae) - STRING interaction network
"mepA" - D-alanyl-D-alanine endopeptidase in Klebsiella pneumoniae
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mepAD-alanyl-D-alanine endopeptidase; functions in hydrolyzing cell wall peptidoglycan; similar to LAS metallopeptidases; forms a dimer in periplasm; Derived by automated computational analysis using gene prediction method- Protein Homology (274 aa)    
Predicted Functional Partners:
JG24_18080
Probable membrane transporter protein; Derived by automated computational analysis using gene prediction method- Protein Homology (269 aa)
        0.977
JG24_18090
Catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis; Derived by automated computational analysis using gene prediction method- Protein Homology (361 aa)
   
   
  0.895
JG24_18075
Putative transporting ATPase; Derived by automated computational analysis using gene prediction method- Protein Homology (182 aa)
   
        0.881
JG24_18070
Uncharacterized protein; Derived by automated computational analysis using gene prediction method- Protein Homology (93 aa)
              0.752
prmB
50S ribosomal protein L3 glutamine methyltransferase; Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (310 aa)
   
        0.731
JG24_09775
Derived by automated computational analysis using gene prediction method- Protein Homology (465 aa)
   
          0.651
JG24_07260
FIG001587- exported protein; Derived by automated computational analysis using gene prediction method- Protein Homology (183 aa)
   
          0.630
JG24_19610
Multidrug resistance protein B; Multidrug MFS transporte; with EmrA is involved in resistance to hydrophobic antibiotics such as nalidixic acid; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the major facilitator superfamily (512 aa)
           
  0.542
JG24_12205
Multidrug MFS transporte; with EmrA is involved in resistance to hydrophobic antibiotics such as nalidixic acid; Derived by automated computational analysis using gene prediction method- Protein Homology (512 aa)
           
  0.542
flk
In Salmonella typhimurium Flk regulates flagellar biosynthesis by inhibition of the flagellar-associated type III secretion system; lowers secretion levels of the anti-sigma28 factor FlgM to the periplasm; inner membrane-anchored protein; Derived by automated computational analysis using gene prediction method- Protein Homology (326 aa)
   
     
  0.540
Your Current Organism:
Klebsiella pneumoniae
NCBI taxonomy Id: 573
Other names: ATCC 13883, Bacillus pneumoniae, Bacterium pneumoniae crouposae, CCUG 225, CIP 82.91, DSM 30104, HAMBI 450, Hyalococcus pneumoniae, IFO 14940, K. pneumoniae, Klebsiella pneumoniae, Klebsiella sp. M-AI-2, Klebsiella sp. PB12, Klebsiella sp. RCE-7, LMG 2095, NBRC 14940, NCTC 9633
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