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glk protein (Klebsiella pneumoniae) - STRING interaction network
"glk" - Glucokinase in Klebsiella pneumoniae
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
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Textmining
[Homology]
Score
glkGlucokinase; Catalyzes the conversion of ATP and D-glucose to ADP and D-glucose 6-phosphate; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the bacterial glucokinase family (321 aa)    
Predicted Functional Partners:
pgi
Glucose-6-phosphate isomerase; Functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the GPI family (549 aa)
   
 
  0.961
JG24_10640
Phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS); catalyzes the phosphorylation of maltose and glucose concomitant with their translocation across the cell membrane; component IIB catalyzes the phosphorylation of the sugar molecule; IIC forms the translocation channel and contains the substrate specific binding site; Derived by automated computational analysis using gene prediction method- Protein Homology (530 aa)
       
  0.952
JG24_08220
PTS system, glucose-specific IIB component / PTS system, glucose-specific IIC component; Phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; Derived by automated computational analysis using gene prediction method- Protein Homology (477 aa)
       
  0.952
zwf
Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone (491 aa)
   
 
  0.938
JG24_15905
4-hydroxy-2-oxoglutarate aldolase @ 2-dehydro-3-deoxyphosphogluconate aldolase; Catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate; Derived by automated computational analysis using gene prediction method- Protein Homology (213 aa)
 
 
  0.932
JG24_06000
Phosphoglucomutase; Catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate; Derived by automated computational analysis using gene prediction method- Protein Homology (546 aa)
       
  0.930
JG24_13535
Beta-glucosidase 6-phospho-beta-glucosidase; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the glycosyl hydrolase 1 family (456 aa)
     
    0.927
galM
Aldose 1-epimerase; Mutarotase; catalyzes the conversion of beta-galactose to the alpha-anomer; links the metabolism of lactose and galactose; Derived by automated computational analysis using gene prediction method- Protein Homology (347 aa)
       
  0.923
JG24_04430
PTS system, glucose-specific IIBC component; Derived by automated computational analysis using gene prediction method- Protein Homology (104 aa)
       
    0.919
JG24_09175
Aldose 1-epimerase family protein YeaD; Derived by automated computational analysis using gene prediction method- Protein Homology (294 aa)
   
 
  0.918
Your Current Organism:
Klebsiella pneumoniae
NCBI taxonomy Id: 573
Other names: ATCC 13883, Bacillus pneumoniae, Bacterium pneumoniae crouposae, CCUG 225, CIP 82.91, DSM 30104, HAMBI 450, Hyalococcus pneumoniae, IFO 14940, K. pneumoniae, Klebsiella pneumoniae, Klebsiella sp. M-AI-2, Klebsiella sp. PB12, Klebsiella sp. RCE-7, LMG 2095, NBRC 14940, NCTC 9633
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