STRINGSTRING
cysZ protein (Klebsiella pneumoniae) - STRING interaction network
"cysZ" - Sulfate transporter CysZ in Klebsiella pneumoniae
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cysZSulfate transporter CysZ; High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway (253 aa)    
Predicted Functional Partners:
JG24_18300
Cell division protein ZipA; Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins (351 aa)
 
          0.743
JG24_18315
Cysteine synthase; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the cysteine synthase/cystathionine beta- synthase family (323 aa)
     
      0.660
JG24_18305
Uncharacterized protein; Derived by automated computational analysis using gene prediction method- Protein Homology (47 aa)
              0.620
hflD
High frequency lysogenization protein HflD homolog; HflD; UPF0274; in Escherichia coli this protein is peripherally associated with the membrane and appears to act with lambda CII protein; in Haemophilus influenzae a knockout of the HI0638 gene affected paracytosis; Derived by automated computational analysis using gene prediction method- Protein Homology (213 aa)
   
          0.582
ligA
DNA ligase; DNA ligase that catalyzes the formation of phosphodiester linkages between 5’-phosphoryl and 3’-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (671 aa)
              0.560
JG24_19315
Derived by automated computational analysis using gene prediction method- Protein Homology (207 aa)
           
  0.526
JG24_02600
Arsenic resistance protein ArsH; Derived by automated computational analysis using gene prediction method- Protein Homology (236 aa)
           
  0.526
JG24_00655
Derived by automated computational analysis using gene prediction method- Protein Homology (237 aa)
           
  0.526
rapA
RNA polymerase-associated protein RapA; Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (968 aa)
 
          0.522
JG24_21685
Putative cytoplasmic protein; Derived by automated computational analysis using gene prediction method- Protein Homology (140 aa)
   
          0.517
Your Current Organism:
Klebsiella pneumoniae
NCBI taxonomy Id: 573
Other names: ATCC 13883, Bacillus pneumoniae, Bacterium pneumoniae crouposae, CCUG 225, CIP 82.91, DSM 30104, HAMBI 450, Hyalococcus pneumoniae, IFO 14940, K. pneumoniae, Klebsiella pneumoniae, Klebsiella sp. M-AI-2, Klebsiella sp. PB12, Klebsiella sp. RCE-7, LMG 2095, NBRC 14940, NCTC 9633
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