STRINGSTRING
cysM protein (Klebsiella pneumoniae) - STRING interaction network
"cysM" - Cysteine synthase B in Klebsiella pneumoniae
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cysMCysteine synthase B; Catalyzes the formation of cysteine from 3-O-acetyl-L-serine and hydrogen sulfide; Derived by automated computational analysis using gene prediction method- Protein Homology (303 aa)    
Predicted Functional Partners:
cysE
Acetyltransferase; Catalyzes the O-acetylation of serine; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the transferase hexapeptide repeat family (273 aa)
 
  0.963
JG24_26145
Catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine; Derived by automated computational analysis using gene prediction method- Protein Homology (386 aa)
  0.944
JG24_21520
Cystathionine gamma-lyase; Derived by automated computational analysis using gene prediction method- Protein Homology (382 aa)
  0.943
cysJ
Sulfite reductase [NADPH] flavoprotein alpha-component; Catalyzes the reduction of sulfite to sulfide in the biosynthesis of L-cysteine from sulfate; a flavoprotein with flavin reductase activity; Derived by automated computational analysis using gene prediction method- Protein Homology (599 aa)
   
  0.942
JG24_21595
Cystathionine beta-lyase; Catalyzes the formation of L-homocysteine from cystathionine; Derived by automated computational analysis using gene prediction method- Protein Homology (395 aa)
  0.936
JG24_20140
Sulfite reductase [NADPH] hemoprotein beta-component; Hemoprotein; NADPH dependent; with the alpha subunit (a flavoprotein) catalyzes the reduction of sulfite to sulfide; Derived by automated computational analysis using gene prediction method- Protein Homology (570 aa)
   
 
  0.932
metH
5-methyltetrahydrofolate--homocysteine methyltransferase; One of two methionine synthases in Escherichia coli; MetH catalyzes a methyl transfer reaction from methyltetrahydrofolate to homocysteine to create methionine; requires zinc for activity; Derived by automated computational analysis using gene prediction method- Protein Homology (1227 aa)
 
 
  0.931
JG24_10635
Cystathionine beta-lyase (CBL) (Beta-cystathionase) (Cysteine lyase) / Maltose regulon modulator; Catalyzes the formation of homocysteine and pyruvate from cystathionine; also acts a a negative regulator for the mal regulon but interacting with the transcriptional activator MalT; Derived by automated computational analysis using gene prediction method- Protein Homology (390 aa)
       
  0.910
JG24_07270
Aminotransferase; Derived by automated computational analysis using gene prediction method- Protein Homology (396 aa)
     
 
  0.902
JG24_03805
Derived by automated computational analysis using gene prediction method- Protein Homology (310 aa)
         
  0.886
Your Current Organism:
Klebsiella pneumoniae
NCBI taxonomy Id: 573
Other names: ATCC 13883, Bacillus pneumoniae, Bacterium pneumoniae crouposae, CCUG 225, CIP 82.91, DSM 30104, HAMBI 450, Hyalococcus pneumoniae, IFO 14940, K. pneumoniae, Klebsiella pneumoniae, Klebsiella sp. M-AI-2, Klebsiella sp. PB12, Klebsiella sp. RCE-7, LMG 2095, NBRC 14940, NCTC 9633
Server load: low (7%) [HD]