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der protein (Klebsiella pneumoniae) - STRING interaction network
"der" - GTPase Der in Klebsiella pneumoniae
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
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[Homology]
Score
derGTPase Der; GTPase that plays an essential role in the late steps of ribosome biogenesis (492 aa)    
Predicted Functional Partners:
JG24_18740
Derived by automated computational analysis using gene prediction method- Protein Homology (392 aa)
      0.940
hisS
Histidine--tRNA ligase; Catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; Derived by automated computational analysis using gene prediction method- Protein Homology (424 aa)
        0.934
JG24_26800
Ribosomal protein; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the universal ribosomal protein uL1 family (234 aa)
   
 
      0.928
JG24_18745
Mlr7403 protein; Derived by automated computational analysis using gene prediction method- Protein Homology (206 aa)
 
   
  0.916
cmk
Cytidylate kinase; Catalyzes the formation of (d)CDP from ATP and (d)CMP; Derived by automated computational analysis using gene prediction method- Protein Homology (227 aa)
   
  0.893
rplD
50S ribosomal protein L4; Forms part of the polypeptide exit tunnel (201 aa)
   
 
      0.849
rplS
50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (115 aa)
 
 
      0.847
rplV
50S ribosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (110 aa)
   
 
  0.846
rplT
50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (118 aa)
   
 
      0.836
rplR
50S ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (117 aa)
   
      0.828
Your Current Organism:
Klebsiella pneumoniae
NCBI taxonomy Id: 573
Other names: ATCC 13883, Bacillus pneumoniae, Bacterium pneumoniae crouposae, CCUG 225, CIP 82.91, DSM 30104, HAMBI 450, Hyalococcus pneumoniae, IFO 14940, K. pneumoniae, Klebsiella pneumoniae, Klebsiella sp. M-AI-2, Klebsiella sp. PB12, Klebsiella sp. RCE-7, LMG 2095, NBRC 14940, NCTC 9633
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