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gshA protein (Klebsiella pneumoniae) - STRING interaction network
"gshA" - Glutamate--cysteine ligase in Klebsiella pneumoniae
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
gshAGlutamate--cysteine ligase; Involved in the first step of glutathione biosynthesis; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily (518 aa)    
Predicted Functional Partners:
JG24_21410
Catalyzes the second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione; Derived by automated computational analysis using gene prediction method- Protein Homology (316 aa)
 
   
  0.965
JG24_19635
Putative membrane protein; Derived by automated computational analysis using gene prediction method- Protein Homology (142 aa)
 
        0.922
JG24_03360
Aminoacyl-histidine dipeptidase (Peptidase D); Catalyzes the hydrolysis of Xaa-His dipeptides; Derived by automated computational analysis using gene prediction method- Protein Homology (485 aa)
         
  0.912
pepN
Membrane alanine aminopeptidase N; Derived by automated computational analysis using gene prediction method- Protein Homology (871 aa)
         
  0.907
ggt
Gamma-glutamyltranspeptidase; Periplasmic enzyme; post-translationally processed into two subunits which are required for wild-type enzyme activity; cleaves the gammaglutamyl linkages of compounds such as glutathione and transfer the gammaglutamyl group to other amino acids and peptides; Derived by automated computational analysis using gene prediction method- Protein Homology (581 aa)
         
  0.905
JG24_12500
Derived by automated computational analysis using gene prediction method- Protein Homology (528 aa)
         
  0.905
pepA
Probable cytosol aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides; Belongs to the peptidase M17 family (503 aa)
     
 
    0.901
pepB
Peptidase B; Probably plays an important role in intracellular peptide degradation (428 aa)
     
 
    0.900
ilvE
Branched-chain-amino-acid aminotransferase; Acts on leucine, isoleucine and valine; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family (309 aa)
         
    0.900
glnA
Forms a homododecamer; forms glutamine from ammonia and glutamate with the conversion of ATP to ADP and phosphate; also functions in the assimilation of ammonia; highly regulated protein controlled by the addition/removal of adenylyl groups by adenylyltransferase from specific tyrosine residues; addition of adenylyl groups results in inactivation of the enzyme; Derived by automated computational analysis using gene prediction method- Protein Homology (469 aa)
         
  0.894
Your Current Organism:
Klebsiella pneumoniae
NCBI taxonomy Id: 573
Other names: ATCC 13883, Bacillus pneumoniae, Bacterium pneumoniae crouposae, CCUG 225, CIP 82.91, DSM 30104, HAMBI 450, Hyalococcus pneumoniae, IFO 14940, K. pneumoniae, Klebsiella pneumoniae, Klebsiella sp. M-AI-2, Klebsiella sp. PB12, Klebsiella sp. RCE-7, LMG 2095, NBRC 14940, NCTC 9633
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