STRINGSTRING
csrA protein (Klebsiella pneumoniae) - STRING interaction network
"csrA" - Carbon storage regulator homolog in Klebsiella pneumoniae
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
csrACarbon storage regulator homolog; Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (61 aa)    
Predicted Functional Partners:
hfq
RNA-binding protein Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (102 aa)
   
 
  0.831
JG24_20205
Histidine kinase; Part of the two-component regulatory system with UvrY; involved in the regulation of carbon metabolism via the csrA/csrB regulatory system; Derived by automated computational analysis using gene prediction method- Protein Homology (916 aa)
         
  0.797
rpoS
RNA polymerase sigma factor RpoS; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor controls a regulon of genes required for protection against external stresses; Derived by automated computational analysis using gene prediction method- Protein Homology (330 aa)
           
  0.774
fis
DNA-binding protein Fis; Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (98 aa)
   
     
  0.677
dksA
C4-type zinc finger protein, DksA/TraR family; Derived by automated computational analysis using gene prediction method- Protein Homology (151 aa)
   
   
  0.647
sirA
BarA-associated response regulator UvrY (= GacA = SirA); In Escherichia coli the protein UvrY is part of a two-component system along with BarA that is needed for efficient switching between glycolytic and gluconeogenic carbon sources possibly by regulating the Csr system; in Salmonella SirA and BarA regulate virulence gene expression also via the Csr system; Derived by automated computational analysis using gene prediction method- Protein Homology (218 aa)
           
  0.646
JG24_22255
Hybrid sensory histidine kinase in two-component regulatory system with EvgA; Derived by automated computational analysis using gene prediction method- Protein Homology (1080 aa)
         
  0.594
JG24_22945
RNA polymerase sigma-54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (477 aa)
 
   
  0.590
JG24_04255
Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation (432 aa)
       
 
  0.587
fur
Ferric uptake regulation protein; Negatively regulates a number of operons that encode enzymes involved in iron transport; activated by manganese; forms a homodimer; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the Fur family (150 aa)
           
  0.574
Your Current Organism:
Klebsiella pneumoniae
NCBI taxonomy Id: 573
Other names: ATCC 13883, Bacillus pneumoniae, Bacterium pneumoniae crouposae, CCUG 225, CIP 82.91, DSM 30104, HAMBI 450, Hyalococcus pneumoniae, IFO 14940, K. pneumoniae, Klebsiella pneumoniae, Klebsiella sp. M-AI-2, Klebsiella sp. PB12, Klebsiella sp. RCE-7, LMG 2095, NBRC 14940, NCTC 9633
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