STRINGSTRING
pcm protein (Klebsiella pneumoniae) - STRING interaction network
"pcm" - Protein-L-isoaspartate O-methyltransferase in Klebsiella pneumoniae
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
Cooccurence
Coexpression
Experiments
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Textmining
[Homology]
Score
pcmProtein-L-isoaspartate O-methyltransferase; Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins (208 aa)    
Predicted Functional Partners:
surE
5’/3’-nucleotidase SurE; Nucleotidase with a broad substrate specificity as it can dephosphorylate various ribo- and deoxyribonucleoside 5’- monophosphates and ribonucleoside 3’-monophosphates with highest affinity to 3’-AMP. Also hydrolyzes polyphosphate (exopolyphosphatase activity) with the preference for short-chain- length substrates (P20-25). Might be involved in the regulation of dNTP and NTP pools, and in the turnover of 3’-mononucleotides produced by numerous intracellular RNases (T1, T2, and F) during the degradation of various RNAs (253 aa)
   
  0.990
JG24_20095
Derived by automated computational analysis using gene prediction method- Protein Homology (236 aa)
   
   
  0.893
truD
tRNA pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (349 aa)
   
   
  0.893
ispF
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate; Derived by automated computational analysis using gene prediction method- Protein Homology (159 aa)
   
   
  0.893
ftsB
Cell division protein FtsB; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (105 aa)
   
        0.850
nlpD
Outer membrane lipoprotein involved in stationary-phase cell survival; similar to LppB virulence determinant from Haemophilus somnus; Derived by automated computational analysis using gene prediction method- Protein Homology (378 aa)
       
  0.800
rpoS
RNA polymerase sigma factor RpoS; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor controls a regulon of genes required for protection against external stresses; Derived by automated computational analysis using gene prediction method- Protein Homology (330 aa)
       
  0.774
JG24_13850
Chloramphenicol acetyltransferase; Derived by automated computational analysis using gene prediction method- Protein Homology (227 aa)
           
  0.651
JG24_04645
Arylesterase; Derived by automated computational analysis using gene prediction method- Protein Homology (207 aa)
           
  0.651
JG24_21695
Type I secretion outer membrane protein, TolC; Derived by automated computational analysis using gene prediction method- Protein Homology (490 aa)
 
   
  0.600
Your Current Organism:
Klebsiella pneumoniae
NCBI taxonomy Id: 573
Other names: ATCC 13883, Bacillus pneumoniae, Bacterium pneumoniae crouposae, CCUG 225, CIP 82.91, DSM 30104, HAMBI 450, Hyalococcus pneumoniae, IFO 14940, K. pneumoniae, Klebsiella pneumoniae, Klebsiella sp. M-AI-2, Klebsiella sp. PB12, Klebsiella sp. RCE-7, LMG 2095, NBRC 14940, NCTC 9633
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