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JG24_20205 protein (Klebsiella pneumoniae) - STRING interaction network
"JG24_20205" - Histidine kinase in Klebsiella pneumoniae
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
JG24_20205Histidine kinase; Part of the two-component regulatory system with UvrY; involved in the regulation of carbon metabolism via the csrA/csrB regulatory system; Derived by automated computational analysis using gene prediction method- Protein Homology (916 aa)    
Predicted Functional Partners:
sirA
BarA-associated response regulator UvrY (= GacA = SirA); In Escherichia coli the protein UvrY is part of a two-component system along with BarA that is needed for efficient switching between glycolytic and gluconeogenic carbon sources possibly by regulating the Csr system; in Salmonella SirA and BarA regulate virulence gene expression also via the Csr system; Derived by automated computational analysis using gene prediction method- Protein Homology (218 aa)
 
  0.979
JG24_16495
FOG- GGDEF domain; Derived by automated computational analysis using gene prediction method- Protein Homology (323 aa)
 
 
  0.948
JG24_23195
Putative lipoprotein; Regulates the degradation of the small RNAs CsrB and CsrC; may function to targate RNase E to specific RNA molecules; Derived by automated computational analysis using gene prediction method- Protein Homology (646 aa)
 
 
  0.924
JG24_08835
Uncharacterized protein; Derived by automated computational analysis using gene prediction method- Protein Homology (594 aa)
 
 
  0.908
JG24_09925
Derived by automated computational analysis using gene prediction method- Protein Homology (404 aa)
 
  0.893
JG24_08880
Uncharacterized protein; Derived by automated computational analysis using gene prediction method- Protein Homology (337 aa)
 
 
  0.885
JG24_01670
Derived by automated computational analysis using gene prediction method- Protein Homology (525 aa)
 
 
  0.884
rcsD
Phosphotransferase RcsD; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsD is a phosphotransfer intermediate between the sensor kinase RcsC and the response regulator RcsB. It acquires a phosphoryl group from RcsC and transfers it to RcsB (885 aa)
 
 
  0.876
JG24_18690
Putative cytochrome C-type biogenesis protein; Derived by automated computational analysis using gene prediction method- Protein Homology (742 aa)
 
 
  0.866
JG24_24325
Protein yhjK; HmsP in Yersinia pestis plays a role in invasion of epithelial cells; the EAL-domain portion of HmsP from Y. pestis shows phosphodiesterase activity which is required for the inhibition of biofilm formation; inner membrane protein; Derived by automated computational analysis using gene prediction method- Protein Homology (668 aa)
 
  0.865
Your Current Organism:
Klebsiella pneumoniae
NCBI taxonomy Id: 573
Other names: ATCC 13883, Bacillus pneumoniae, Bacterium pneumoniae crouposae, CCUG 225, CIP 82.91, DSM 30104, HAMBI 450, Hyalococcus pneumoniae, IFO 14940, K. pneumoniae, Klebsiella pneumoniae, Klebsiella sp. M-AI-2, Klebsiella sp. PB12, Klebsiella sp. RCE-7, LMG 2095, NBRC 14940, NCTC 9633
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