STRINGSTRING
JG24_20745 protein (Klebsiella pneumoniae) - STRING interaction network
"JG24_20745" - 2-acylglycerophosphoethanolamine acyltransferase / Acyl-[acyl-carrier-protein] synthetase in Klebsiella pneumoniae
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
JG24_207452-acylglycerophosphoethanolamine acyltransferase / Acyl-[acyl-carrier-protein] synthetase; Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium. Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1; Derived by automated computational analysis using gene prediction method- Protein Homology (719 aa)    
Predicted Functional Partners:
JG24_20740
Lysophospholipid transporter LplT; Derived by automated computational analysis using gene prediction method- Protein Homology (397 aa)
   
  0.990
psd
Phosphatidylserine decarboxylase proenzyme; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer); Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily (320 aa)
   
 
  0.932
JG24_26595
Lysophospholipase L2; Derived by automated computational analysis using gene prediction method- Protein Homology (330 aa)
 
 
  0.931
JG24_26570
Phospholipase A1, Outer membrane phospholipase A; Catalyzes the hydrolysis of phosphatidylcholine; Derived by automated computational analysis using gene prediction method- Protein Homology (286 aa)
         
  0.910
acpS
Holo-[acyl-carrier-protein] synthase; Transfers the 4’-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family (126 aa)
 
     
  0.848
pssA
CDP-diacylglycerol--serine O-phosphatidyltransferase; Catalyzes de novo synthesis of phosphatidylserine from CDP-diacylglycerol and L-serine which leads eventually to the production of phosphatidylethanolamine; bounds to the ribosome; Derived by automated computational analysis using gene prediction method- Protein Homology (451 aa)
   
  0.835
JG24_05320
Catalyzes the oxidation of choline to betaine aldehyde and betain aldehyde to glycine betaine; Derived by automated computational analysis using gene prediction method- Protein Homology (554 aa)
       
  0.807
fadB
Multifunctional fatty acid oxidation complex subunit alpha; Includes enoyl-CoA hydratase, delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase, 3-hydroxyacyl-CoA dehydrogenase, and 3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities; forms a heterotetramer with FadA; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids; Derived by automated computational analysis using gene prediction method- Protein Homology (729 aa)
   
 
  0.765
fadJ
Multifunctional enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase/3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities- forms a heterotetramer with FadI; similar to FadA2B2 complex; involved in the anaerobic degradation of long and medium-chain fatty acids in the presence of nitrate; Derived by automated computational analysis using gene prediction method- Protein Homology (714 aa)
   
 
  0.765
JG24_10370
Aldehyde dehydrogenase, PaaZ; Catalyzes the ring cleavage reaction in phenylacetate degradation and the formation of 3-hydroxyacyl-CoA from crotonyl-CoA; Derived by automated computational analysis using gene prediction method- Protein Homology (681 aa)
   
 
  0.708
Your Current Organism:
Klebsiella pneumoniae
NCBI taxonomy Id: 573
Other names: ATCC 13883, Bacillus pneumoniae, Bacterium pneumoniae crouposae, CCUG 225, CIP 82.91, DSM 30104, HAMBI 450, Hyalococcus pneumoniae, IFO 14940, K. pneumoniae, Klebsiella pneumoniae, Klebsiella sp. M-AI-2, Klebsiella sp. PB12, Klebsiella sp. RCE-7, LMG 2095, NBRC 14940, NCTC 9633
Server load: low (9%) [HD]