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ygfZ protein (Klebsiella pneumoniae) - STRING interaction network
"ygfZ" - Folate-dependent protein for Fe/S cluster synthesis/repair in oxidative stress in Klebsiella pneumoniae
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
ygfZFolate-dependent protein for Fe/S cluster synthesis/repair in oxidative stress; Physiological role is not clear; not essential for growth but mutants grow poorly; mutations suppress hda null mutations; may be involved in regulation of ATP-DnaA levels; may also be involved in regulation of tRNA modifications; can bind folic acid and tetrahydrofolate; forms a three domain ring-like structure with a central channel; structurally similar to DMGO protein from A. globiformis; shows sequence similarity to yeast CAF17 transcriptional regulato; Hda supressor; Derived by automated computational [...] (327 aa)    
Predicted Functional Partners:
holA
DNA polymerase III subunit delta; Required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA; Derived by automated computational analysis using gene prediction method- Protein Homology (343 aa)
   
   
  0.733
erpA
Iron-sulfur cluster insertion protein ErpA; Essential respiratory protein A; may be involved in the transfer of iron-sulfur clusters; essential for growth using oxygen or alternate electron acceptors; Derived by automated computational analysis using gene prediction method- Protein Homology (114 aa)
 
 
  0.705
JG24_08210
DNA polymerase III delta prime subunit; Catalyzes the DNA-template-directed extension of the 3’-end of a DNA strand; the delta’ subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA; Derived by automated computational analysis using gene prediction method- Protein Homology (334 aa)
 
   
  0.695
JG24_21200
YgfY COG2938; Derived by automated computational analysis using gene prediction method- Protein Homology (88 aa)
   
        0.623
JG24_13690
Glutaredoxin; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the glutaredoxin family. Monothiol subfamily (115 aa)
   
     
  0.618
rpoD
RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth (613 aa)
 
   
  0.587
nfuA
Fe/S biogenesis protein NfuA; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins (191 aa)
   
 
  0.569
JG24_09440
Membrane protein YciC, linked to IspA; Derived by automated computational analysis using gene prediction method- Protein Homology (247 aa)
   
          0.560
secE
Protein translocase subunit SecE; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation (127 aa)
   
     
  0.554
JG24_21195
Uncharacterized protein; Derived by automated computational analysis using gene prediction method- Protein Homology (136 aa)
 
        0.546
Your Current Organism:
Klebsiella pneumoniae
NCBI taxonomy Id: 573
Other names: ATCC 13883, Bacillus pneumoniae, Bacterium pneumoniae crouposae, CCUG 225, CIP 82.91, DSM 30104, HAMBI 450, Hyalococcus pneumoniae, IFO 14940, K. pneumoniae, Klebsiella pneumoniae, Klebsiella sp. M-AI-2, Klebsiella sp. PB12, Klebsiella sp. RCE-7, LMG 2095, NBRC 14940, NCTC 9633
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