STRINGSTRING
JG24_21275 protein (Klebsiella pneumoniae) - STRING interaction network
"JG24_21275" - Oxygenase that introduces the hydroxyl group at carbon four of 2-octaprenyl-6-methoxyphenol resulting in the formation of 2-octaprenyl-6-methoxy-1,4-benzoquinone in Klebsiella pneumoniae
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
JG24_21275Oxygenase that introduces the hydroxyl group at carbon four of 2-octaprenyl-6-methoxyphenol resulting in the formation of 2-octaprenyl-6-methoxy-1,4-benzoquinone; Derived by automated computational analysis using gene prediction method- Protein Homology (392 aa)    
Predicted Functional Partners:
JG24_17660
3-demethylubiquinol 3-O-methyltransferase; Involved in ubiquinone biosynthesis; Derived by automated computational analysis using gene prediction method- Protein Homology (242 aa)
 
  0.989
ubiE
Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (251 aa)
   
 
  0.975
JG24_21280
Xaa-Pro aminopeptidase; Exopeptidase able to cleave the peptide bond of the last amino acid if linked to a proline residue; substrate can be as short as a dipeptide; Derived by automated computational analysis using gene prediction method- Protein Homology (438 aa)
   
   
  0.925
JG24_21270
2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Derived by automated computational analysis using gene prediction method- Protein Homology (400 aa)
 
   
0.909
ubiA
4-hydroxybenzoate octaprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate (288 aa)
   
   
  0.879
JG24_21285
UPF0149 exported protein YgfB; The crystal structure of Haemophilus influenzae HI0817 showed that this protein forms dimers; function unknown; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the UPF0149 family (194 aa)
   
   
  0.842
zapA
Cell division protein ZapA; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (109 aa)
 
          0.696
JG24_22870
Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the FPP/GGPP synthase family (323 aa)
 
 
  0.660
JG24_26680
3-polyprenyl-4-hydroxybenzoate carboxy-lyase; Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the UbiD family (489 aa)
   
   
  0.655
JG24_19230
Putative oligoketide cyclase/dehydratase or lipid transport protein YfjG; Derived by automated computational analysis using gene prediction method- Protein Homology (145 aa)
   
     
  0.641
Your Current Organism:
Klebsiella pneumoniae
NCBI taxonomy Id: 573
Other names: ATCC 13883, Bacillus pneumoniae, Bacterium pneumoniae crouposae, CCUG 225, CIP 82.91, DSM 30104, HAMBI 450, Hyalococcus pneumoniae, IFO 14940, K. pneumoniae, Klebsiella pneumoniae, Klebsiella sp. M-AI-2, Klebsiella sp. PB12, Klebsiella sp. RCE-7, LMG 2095, NBRC 14940, NCTC 9633
Server load: low (8%) [HD]