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JG24_21410 protein (Klebsiella pneumoniae) - STRING interaction network
"JG24_21410" - Catalyzes the second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione in Klebsiella pneumoniae
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
JG24_21410Catalyzes the second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione; Derived by automated computational analysis using gene prediction method- Protein Homology (316 aa)    
Predicted Functional Partners:
gshA
Glutamate--cysteine ligase; Involved in the first step of glutathione biosynthesis; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily (518 aa)
 
   
  0.965
JG24_24255
Catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family (450 aa)
     
  0.956
JG24_13595
Glutathione S-transferase; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the GST superfamily (201 aa)
   
 
  0.926
JG24_06825
Glutathione S-transferase; Derived by automated computational analysis using gene prediction method- Protein Homology (208 aa)
   
 
  0.920
btuE
Thioredoxin/glutathione peroxidase BtuE; Non-specific peroxidase that can use thioredoxin or glutathione as a reducing agent (183 aa)
     
 
  0.918
JG24_09145
Glutathione peroxidase; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the glutathione peroxidase family (160 aa)
     
 
  0.918
pepN
Membrane alanine aminopeptidase N; Derived by automated computational analysis using gene prediction method- Protein Homology (871 aa)
     
 
  0.914
ggt
Gamma-glutamyltranspeptidase; Periplasmic enzyme; post-translationally processed into two subunits which are required for wild-type enzyme activity; cleaves the gammaglutamyl linkages of compounds such as glutathione and transfer the gammaglutamyl group to other amino acids and peptides; Derived by automated computational analysis using gene prediction method- Protein Homology (581 aa)
         
  0.910
JG24_12500
Derived by automated computational analysis using gene prediction method- Protein Homology (528 aa)
         
  0.910
JG24_27345
Glutathione S-transferase; Derived by automated computational analysis using gene prediction method- Protein Homology (222 aa)
       
  0.908
Your Current Organism:
Klebsiella pneumoniae
NCBI taxonomy Id: 573
Other names: ATCC 13883, Bacillus pneumoniae, Bacterium pneumoniae crouposae, CCUG 225, CIP 82.91, DSM 30104, HAMBI 450, Hyalococcus pneumoniae, IFO 14940, K. pneumoniae, Klebsiella pneumoniae, Klebsiella sp. M-AI-2, Klebsiella sp. PB12, Klebsiella sp. RCE-7, LMG 2095, NBRC 14940, NCTC 9633
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