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dkgA protein (Klebsiella pneumoniae) - STRING interaction network
"dkgA" - Methylglyoxal reductase/beta-keto ester reductase in Klebsiella pneumoniae
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
dkgAMethylglyoxal reductase/beta-keto ester reductase; catalyzes the reduction of 2,5-diketo-D-gluconic acid to 2-keto-L-gulonic acid; also catalyzes the reduction of methylglyoxal, ethyl-2-methylacetoacetate and ethyl-acetoacetate; Derived by automated computational analysis using gene prediction method- Protein Homology (275 aa)    
Predicted Functional Partners:
JG24_21610
Hypothetical oxidoreductase YqhD; Derived by automated computational analysis using gene prediction method- Protein Homology (387 aa)
     
 
  0.802
JG24_12140
Derived by automated computational analysis using gene prediction method- Protein Homology (385 aa)
     
 
  0.610
JG24_10495
Aldo-keto reductase; Derived by automated computational analysis using gene prediction method- Protein Homology (332 aa)
 
   
  0.602
JG24_25725
Ribose ABC transport system, periplasmic ribose-binding protein RbsB (TC 3.A.1.2.1); Periplasmic substrate-binding component of the ATP-dependent ribose transport system; Derived by automated computational analysis using gene prediction method- Protein Homology (296 aa)
           
  0.532
JG24_04995
Oxidoreductase; Derived by automated computational analysis using gene prediction method- Protein Homology (317 aa)
 
   
  0.473
JG24_21605
Transcriptional regulator YqhC, positively regulates YqhD and DkgA; Derived by automated computational analysis using gene prediction method- Protein Homology (299 aa)
   
   
  0.444
nnrD
ADP-dependent (S)-NAD(P)H-hydrate dehydratase; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (508 aa)
   
      0.425
JG24_13710
Putative transport protein; Derived by automated computational analysis using gene prediction method- Protein Homology (388 aa)
 
        0.418
JG24_03220
Putative drug efflux protein; Derived by automated computational analysis using gene prediction method- Protein Homology (396 aa)
 
        0.410
JG24_10500
Derived by automated computational analysis using gene prediction method- Protein Homology (395 aa)
 
        0.408
Your Current Organism:
Klebsiella pneumoniae
NCBI taxonomy Id: 573
Other names: ATCC 13883, Bacillus pneumoniae, Bacterium pneumoniae crouposae, CCUG 225, CIP 82.91, DSM 30104, HAMBI 450, Hyalococcus pneumoniae, IFO 14940, K. pneumoniae, Klebsiella pneumoniae, Klebsiella sp. M-AI-2, Klebsiella sp. PB12, Klebsiella sp. RCE-7, LMG 2095, NBRC 14940, NCTC 9633
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