STRINGSTRING
patA protein (Klebsiella pneumoniae) - STRING interaction network
"patA" - Putrescine aminotransferase in Klebsiella pneumoniae
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
patAPutrescine aminotransferase; Catalyzes the aminotransferase reaction from putrescine to 2-oxoglutarate, leading to glutamate and 4-aminobutanal, which spontaneously cyclizes to form 1-pyrroline. Is also able to transaminate cadaverine and, in lower extent, spermidine, but not ornithine (459 aa)    
Predicted Functional Partners:
JG24_13335
4-aminobutyraldehyde dehydrogenase; Catalyzes the formation of 4-aminobutanoate from 4-aminobutanal; involved in putrescine degradation; Derived by automated computational analysis using gene prediction method- Protein Homology (475 aa)
   
  0.959
JG24_21370
Agmatinase; Catalyzes the formation of putrescine from agmatine; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the arginase family (306 aa)
   
  0.957
JG24_07620
Gamma-glutamyl-putrescine synthetase; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the glutamine synthetase family (473 aa)
 
 
  0.923
JG24_21500
Ornithine decarboxylase; Derived by automated computational analysis using gene prediction method- Protein Homology (712 aa)
   
 
  0.914
JG24_30075
Spermidine synthase; Derived by automated computational analysis using gene prediction method- Protein Homology (286 aa)
     
 
  0.912
JG24_11385
Catalyzes the formation of N(1)- and N(8)-acetylspermidine from spermidine; Derived by automated computational analysis using gene prediction method- Protein Homology (186 aa)
         
  0.910
argA
Amino-acid acetyltransferase; Catalyzes the formation of N-acetyl-L-glutamate from L-glutamate and acetyl-CoA in arginine biosynthesis; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the acetyltransferase family. ArgA subfamily (443 aa)
 
   
  0.765
clpS
ATP-dependent Clp protease adapter protein ClpS; Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (105 aa)
       
 
  0.747
gltB
Glutamate synthase [NADPH] large chain; Catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate; Derived by automated computational analysis using gene prediction method- Protein Homology (1486 aa)
   
   
  0.696
JG24_26210
N-acetyl-gamma-glutamyl-phosphate reductase; Derived by automated computational analysis using gene prediction method- Protein Homology (334 aa)
 
   
  0.651
Your Current Organism:
Klebsiella pneumoniae
NCBI taxonomy Id: 573
Other names: ATCC 13883, Bacillus pneumoniae, Bacterium pneumoniae crouposae, CCUG 225, CIP 82.91, DSM 30104, HAMBI 450, Hyalococcus pneumoniae, IFO 14940, K. pneumoniae, Klebsiella pneumoniae, Klebsiella sp. M-AI-2, Klebsiella sp. PB12, Klebsiella sp. RCE-7, LMG 2095, NBRC 14940, NCTC 9633
Server load: low (5%) [HD]