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lsrG protein (Klebsiella pneumoniae) - STRING interaction network
"lsrG" - (4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase in Klebsiella pneumoniae
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
Cooccurence
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[Homology]
Score
lsrG(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase; Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle. Catalyzes the conversion of (4S)-4-hydroxy-5- phosphonooxypentane-2,3-dione (P-DPD) to 3-hydroxy-5- phosphonooxypentane-2,4-dione (P-HPD); Belongs to the LsrG family (98 aa)    
Predicted Functional Partners:
JG24_22380
Autoinducer 2 (AI-2) aldolase LsrF; Involved in autoinducer 2 transport and processing; Derived by automated computational analysis using gene prediction method- Protein Homology (295 aa)
 
 
  0.995
JG24_22385
Autoinducer 2 (AI-2) ABC transport system,periplasmic AI-2 binding protein LsrB; With lsrACD is involved in the transport of autoinducer 2 into the cell; Derived by automated computational analysis using gene prediction method- Protein Homology (337 aa)
 
   
  0.994
JG24_22390
Autoinducer 2 (AI-2) ABC transport system,membrane channel protein LsrD; With IsrABC is involved with autoinducer 2 import; Derived by automated computational analysis using gene prediction method- Protein Homology (334 aa)
 
   
  0.975
JG24_22395
With LsrADB is involved in the transport of autoindiuce 2; Derived by automated computational analysis using gene prediction method- Protein Homology (344 aa)
 
   
  0.962
JG24_22400
Autoinducer 2 (AI-2) ABC transport system, fused AI2 transporter subunits and ATP-binding component; With LsrCDB is involved in the transport of autoindiuce 2; Derived by automated computational analysis using gene prediction method- Protein Homology (495 aa)
 
   
  0.959
JG24_22410
Derived by automated computational analysis using gene prediction method- Protein Homology (532 aa)
 
   
  0.950
JG24_22405
Regulates the transcription of lsr genes; involved in autoinducer 2 uptake, biofilm formation and stress responses; Derived by automated computational analysis using gene prediction method- Protein Homology (323 aa)
 
   
  0.893
JG24_26025
Predicted L-rhamnose ABC transporter,substrate-binding component; Derived by automated computational analysis using gene prediction method- Protein Homology (328 aa)
 
   
  0.766
tqsA
Putative transport protein; Transport of quorum-sensing signal; mutations in this gene alters the transport of the quorum-sensing signal autoinducer 2 (AI-2) which affects expression of a large number of genes; Derived by automated computational analysis using gene prediction method- Protein Homology (344 aa)
           
  0.651
xylF
Xylose ABC transporter, periplasmic xylose-binding protein XylF; Periplasmic substrate-binding component of the ATP-dependent xylose transport system; high affinity; Derived by automated computational analysis using gene prediction method- Protein Homology (331 aa)
           
  0.519
Your Current Organism:
Klebsiella pneumoniae
NCBI taxonomy Id: 573
Other names: ATCC 13883, Bacillus pneumoniae, Bacterium pneumoniae crouposae, CCUG 225, CIP 82.91, DSM 30104, HAMBI 450, Hyalococcus pneumoniae, IFO 14940, K. pneumoniae, Klebsiella pneumoniae, Klebsiella sp. M-AI-2, Klebsiella sp. PB12, Klebsiella sp. RCE-7, LMG 2095, NBRC 14940, NCTC 9633
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