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garL protein (Klebsiella pneumoniae) - STRING interaction network
"garL" - 5-keto-4-deoxy-D-glucarate aldolase in Klebsiella pneumoniae
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
garL5-keto-4-deoxy-D-glucarate aldolase; Catalyzes the reversible retro-aldol cleavage of both 5- keto-4-deoxy-D-glucarate and 2-keto-3-deoxy-D-glucarate to pyruvate and tartronic semialdehyde; Belongs to the HpcH/HpaI aldolase family. KDGluc aldolase subfamily (256 aa)    
Predicted Functional Partners:
garR
2-hydroxy-3-oxopropionate reductase; Catalyzes the reduction of tatronate semialdehyde to D- glycerate (296 aa)
 
 
  0.973
gudD
Glucarate dehydratase; Catalyzes the formation of 5-keto-4-deoxy-D-glucarate from glucarate; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the mandelate racemase/muconate lactonizing enzyme family (446 aa)
 
 
  0.932
garD
D-galactarate dehydratase; Catalyzes the formation of 5-dehydro-4-deoxy-D-glucarate from D-galactarate; Derived by automated computational analysis using gene prediction method- Protein Homology (523 aa)
 
 
    0.925
JG24_29020
2-oxo-hepta-3-ene-1,7-dioic acid hydratase; Derived by automated computational analysis using gene prediction method- Protein Homology (267 aa)
   
  0.784
JG24_22555
Glycerate-2-kinase; Derived by automated computational analysis using gene prediction method- Protein Homology (381 aa)
   
   
  0.618
JG24_29030
3,4-dihydroxyphenylacetate 2,3-dioxygenase; Derived by automated computational analysis using gene prediction method- Protein Homology (285 aa)
 
   
  0.592
JG24_29025
5-carboxymethyl-2-hydroxymuconate delta-isomerase; Catalyzes the formation of 5-oxo-pent-3-ene-1,2,5-tricarboxylic acid from 5-carboxymethyl-2-hydroxy-muconic acid; Derived by automated computational analysis using gene prediction method- Protein Homology (126 aa)
 
   
  0.508
JG24_29040
Derived by automated computational analysis using gene prediction method- Protein Homology (254 aa)
 
   
  0.470
JG24_14530
Derived by automated computational analysis using gene prediction method- Protein Homology (268 aa)
   
  0.463
JG24_29045
Derived by automated computational analysis using gene prediction method- Protein Homology (210 aa)
 
   
  0.437
Your Current Organism:
Klebsiella pneumoniae
NCBI taxonomy Id: 573
Other names: ATCC 13883, Bacillus pneumoniae, Bacterium pneumoniae crouposae, CCUG 225, CIP 82.91, DSM 30104, HAMBI 450, Hyalococcus pneumoniae, IFO 14940, K. pneumoniae, Klebsiella pneumoniae, Klebsiella sp. M-AI-2, Klebsiella sp. PB12, Klebsiella sp. RCE-7, LMG 2095, NBRC 14940, NCTC 9633
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